% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Tarakanchikova:148726,
      author       = {Y. Tarakanchikova and J. Alzubi and V. Pennucci and M.
                      Follo and B. Kochergin and A. Muslimov and I. Skovorodkin
                      and S. Vainio and M. N. Antipina and V. Atkin and A. Popov
                      and I. Meglinski and T. Cathomen and T. I. Cornu and D. A.
                      Gorin and G. B. Sukhorukov and I. Nazarenko$^*$},
      title        = {{B}iodegradable {N}anocarriers {R}esembling {E}xtracellular
                      {V}esicles {D}eliver {G}enetic {M}aterial with the {H}ighest
                      {E}fficiency to {V}arious {C}ell {T}ypes.},
      journal      = {Small},
      volume       = {Dec},
      issn         = {1613-6829},
      address      = {Weinheim},
      publisher    = {Wiley-VCH},
      reportid     = {DKFZ-2019-03252},
      pages        = {e1904880},
      year         = {2019},
      note         = {Small. 2019 Dec 16:e1904880},
      abstract     = {Efficient delivery of genetic material to primary cells
                      remains challenging. Here, efficient transfer of genetic
                      material is presented using synthetic biodegradable
                      nanocarriers, resembling extracellular vesicles in their
                      biomechanical properties. This is based on two main
                      technological achievements: generation of soft biodegradable
                      polyelectrolyte capsules in nanosize and efficient
                      application of the nanocapsules for co-transfer of different
                      RNAs to tumor cell lines and primary cells, including
                      hematopoietic progenitor cells and primary T cells. Near to
                      $100\%$ efficiency is reached using only 2.5 × 10-4 pmol of
                      siRNA, and 1 × 10-3 nmol of mRNA per cell, which is several
                      magnitude orders below the amounts reported for any of
                      methods published so far. The data show that biodegradable
                      nanocapsules represent a universal and highly efficient
                      biomimetic platform for the transfer of genetic material
                      with the utmost potential to revolutionize gene transfer
                      technology in vitro and in vivo.},
      cin          = {L601},
      ddc          = {540},
      cid          = {I:(DE-He78)L601-20160331},
      pnm          = {899 - ohne Topic (POF3-899)},
      pid          = {G:(DE-HGF)POF3-899},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31840408},
      doi          = {10.1002/smll.201904880},
      url          = {https://inrepo02.dkfz.de/record/148726},
}