TY  - JOUR
AU  - Heath, Alicia K
AU  - Muller, David C
AU  - van den Brandt, Piet A
AU  - Papadimitriou, Nikos
AU  - Critselis, Elena
AU  - Gunter, Marc
AU  - Vineis, Paolo
AU  - Weiderpass, Elisabete
AU  - Fagherazzi, Guy
AU  - Boeing, Heiner
AU  - Ferrari, Pietro
AU  - Olsen, Anja
AU  - Tjønneland, Anne
AU  - Arveux, Patrick
AU  - Boutron-Ruault, Marie-Christine
AU  - Mancini, Francesca Romana
AU  - Kühn, Tilman
AU  - Turzanski-Fortner, Renée
AU  - Schulze, Matthias B
AU  - Karakatsani, Anna
AU  - Thriskos, Paschalis
AU  - Trichopoulou, Antonia
AU  - Masala, Giovanna
AU  - Contiero, Paolo
AU  - Ricceri, Fulvio
AU  - Panico, Salvatore
AU  - Bueno-de-Mesquita, Bas
AU  - Bakker, Marije F
AU  - van Gils, Carla H
AU  - Olsen, Karina Standahl
AU  - Skeie, Guri
AU  - Lasheras, Cristina
AU  - Agudo, Antonio
AU  - Rodríguez-Barranco, Miguel
AU  - Sánchez, Maria-José
AU  - Amiano, Pilar
AU  - Chirlaque, María-Dolores
AU  - Barricarte, Aurelio
AU  - Drake, Isabel
AU  - Ericson, Ulrika
AU  - Johansson, Ingegerd
AU  - Winkvist, Anna
AU  - Key, Tim
AU  - Freisling, Heinz
AU  - His, Mathilde
AU  - Huybrechts, Inge
AU  - Christakoudi, Sofia
AU  - Ellingjord-Dale, Merete
AU  - Riboli, Elio
AU  - Tsilidis, Konstantinos K
AU  - Tzoulaki, Ioanna
TI  - Nutrient-wide association study of 92 foods and nutrients and breast cancer risk.
JO  - Breast cancer research
VL  - 22
IS  - 1
SN  - 1465-542X
CY  - London
PB  - BioMed Central
M1  - DKFZ-2020-00202
SP  - 5
PY  - 2020
AB  - Several dietary factors have been reported to be associated with risk of breast cancer, but to date, unequivocal evidence only exists for alcohol consumption. We sought to systematically assess the association between intake of 92 foods and nutrients and breast cancer risk using a nutrient-wide association study.Using data from 272,098 women participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, we assessed dietary intake of 92 foods and nutrients estimated by dietary questionnaires. Cox regression was used to quantify the association between each food/nutrient and risk of breast cancer. A false discovery rate (FDR) of 0.05 was used to select the set of foods and nutrients to be replicated in the independent Netherlands Cohort Study (NLCS).Six foods and nutrients were identified as associated with risk of breast cancer in the EPIC study (10,979 cases). Higher intake of alcohol overall was associated with a higher risk of breast cancer (hazard ratio (HR) for a 1 SD increment in intake = 1.05, 95
LB  - PUB:(DE-HGF)16
C6  - pmid:31931881
DO  - DOI:10.1186/s13058-019-1244-7
UR  - https://inrepo02.dkfz.de/record/153120
ER  -