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@ARTICLE{Thong:153439,
      author       = {M. Thong$^*$ and L. Jansen$^*$ and J. Chang-Claude$^*$ and
                      M. Hoffmeister$^*$ and H. Brenner$^*$ and V. Arndt$^*$},
      title        = {{A}ssociation of laparoscopic colectomy versus open
                      colectomy on the long-term health-related quality of life of
                      colon cancer survivors.},
      journal      = {Surgical endoscopy and other interventional techniques},
      volume       = {34},
      number       = {12},
      issn         = {0930-2794},
      address      = {Heidelberg]},
      publisher    = {Springer},
      reportid     = {DKFZ-2020-00290},
      pages        = {5593-5603},
      year         = {2020},
      note         = {#EA:C071#LA:C071#2020 Dec;34(12):5593-5603ISSN: 0930-2794
                      (Print) 1432-2218 (Electronic) 0930-2794 (Linking)},
      abstract     = {Laparoscopic colectomy (LC) is a less invasive alternative
                      to open colectomy (OC) in the treatment of stage I-III colon
                      cancer. Research on the long-term (5-year post-diagnosis)
                      health-related quality of life (HRQOL) of LC patients is
                      scarce. Our study aimed to compare the long-term HRQOL and
                      psychological well-being of stage I-III colon cancer
                      survivors treated either with LC or OC.This study used a
                      German population-based cohort of patients treated with
                      either LC (n = 86) or OC (n = 980). LC patients were
                      matched to OC patients using a propensity score. At 5-year
                      follow-up, patients completed assessments on HRQOL (EORTC
                      QLQ-C30 and EORTC QLQ-CR29) and psychological well-being
                      (distress and disease/treatment burden). Least square mean
                      scores of HRQOL were derived using linear regression.
                      Proportions of patients with moderate/high distress and
                      disease/treatment burden were compared with Chi-square
                      tests.In total, 81 LC patients were matched to 156 OC
                      patients. Generally, LC patients had HRQOL comparable to OC
                      patients, albeit LC patients reported significantly better
                      body image (87.1 versus 81.0, p = 0.03). Distress levels
                      were generally low and comparable between the two groups,
                      even though LC patients were more likely to experience
                      disease recurrence $(16\%$ versus $7\%,$ p = 0.02) than
                      OC patients. OC patients were more likely to feel
                      moderate/high levels of burden associated with the treatment
                      $(72\%$ versus $56\%,$ p = 0.01) and the time after
                      treatment completion $(43\%$ versus $28\%,$ p = 0.02).LC
                      patients reported comparable long-term HRQOL outcomes but
                      higher levels of psychological well-being than OC patients 5
                      years after diagnosis, even though LC was associated with
                      higher risk of disease recurrence.},
      cin          = {C071 / C070 / C020 / C120 / HD01},
      ddc          = {610},
      cid          = {I:(DE-He78)C071-20160331 / I:(DE-He78)C070-20160331 /
                      I:(DE-He78)C020-20160331 / I:(DE-He78)C120-20160331 /
                      I:(DE-He78)HD01-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31993822},
      doi          = {10.1007/s00464-019-07360-2},
      url          = {https://inrepo02.dkfz.de/record/153439},
}