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@ARTICLE{Finke:153690,
      author       = {I. Finke$^*$ and G. Behrens$^*$ and L. Schwettmann and M.
                      Gerken and R. Pritzkuleit and B. Holleczek and H.
                      Brenner$^*$ and L. Jansen$^*$},
      collaboration = {G. C. S. W. Group},
      title        = {{S}ocioeconomic differences and lung cancer survival in
                      {G}ermany: {I}nvestigation based on population-based
                      clinical cancer registration.},
      journal      = {Lung cancer},
      volume       = {142},
      issn         = {0169-5002},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2020-00394},
      pages        = {1 - 8},
      year         = {2020},
      note         = {Volume 142, April 2020, Pages 1-8#EA:C070#LA:C070#},
      abstract     = {Studies from several countries reported socioeconomic
                      inequalities in lung cancer survival. Hypothesized reasons
                      are differences in cancer care or tumor characteristics. We
                      investigated associations of small-area deprivation and lung
                      cancer survival in Germany and the possible impact of
                      differences in patient, tumor or treatment factors.Patients
                      registered with a primary tumor of the lung between
                      2000-2015 in three German population-based clinical cancer
                      registries were included. Area-based socioeconomic
                      deprivation on municipality level was measured with the
                      categorized German Index of Multiple Deprivation.
                      Association of deprivation with overall survival was
                      investigated with Cox regression models.Overall, 22,905
                      patients were included. Five-year overall survival from the
                      least to the most deprived quintile were $17.2\%,$ $15.9\%,$
                      $16.7\%,$ $15.7\%,$ and $14.4\%.$ After adjustment for
                      patient and tumor factors, the most deprived group had a
                      lower survival compared to the least deprived group (Hazard
                      Ratio (HR) 1.06, $95\%$ confidence interval (CI) 1.01-1.11).
                      Subgroup analyses revealed lower survival in the most
                      deprived compared to the least deprived quintile in patients
                      with stage I-III [HR: 1.14, $95\%$ CI: 1.06-1.22]. The
                      association persisted when restricting to patients receiving
                      surgery but was attenuated for subgroups receiving either
                      chemotherapy or radiotherapy.Our results indicate
                      differences in lung cancer survival according to area
                      deprivation in Germany, which were more pronounced in
                      patients with I-III stage cancer. Future research should
                      address in more detail the underlying reasons for the
                      observed inequalities and possible approaches to overcome
                      them.},
      cin          = {C070 / C120 / HD01},
      ddc          = {610},
      cid          = {I:(DE-He78)C070-20160331 / I:(DE-He78)C120-20160331 /
                      I:(DE-He78)HD01-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32044589},
      doi          = {10.1016/j.lungcan.2020.01.021},
      url          = {https://inrepo02.dkfz.de/record/153690},
}