%0 Journal Article
%A Rodriguez-Martin, Bernardo
%A Alvarez, Eva G
%A Baez-Ortega, Adrian
%A Zamora, Jorge
%A Supek, Fran
%A Demeulemeester, Jonas
%A Santamarina, Martin
%A Ju, Young Seok
%A Temes, Javier
%A Garcia-Souto, Daniel
%A Detering, Harald
%A Li, Yilong
%A Rodriguez-Castro, Jorge
%A Dueso-Barroso, Ana
%A Bruzos, Alicia L
%A Dentro, Stefan
%A Blanco, Miguel G
%A Contino, Gianmarco
%A Ardeljan, Daniel
%A Tojo, Marta
%A Roberts, Nicola D
%A Zumalave, Sonia
%A Edwards, Paul A W
%A Weischenfeldt, Joachim
%A Puiggròs, Montserrat
%A Chong, Zechen
%A Chen, Ken
%A Lee, Eunjung Alice
%A Wala, Jeremiah A
%A Raine, Keiran
%A Butler, Adam
%A Waszak, Sebastian M
%A Navarro, Fabio C P
%A Schumacher, Steven E
%A Monlong, Jean
%A Maura, Francesco
%A Bolli, Niccolo
%A Bourque, Guillaume
%A Gerstein, Mark
%A Park, Peter J
%A Wedge, David C
%A Beroukhim, Rameen
%A Torrents, David
%A Korbel, Jan O
%A Martincorena, Inigo
%A Fitzgerald, Rebecca C
%A Van Loo, Peter
%A Kazazian, Haig H
%A Burns, Kathleen H
%A Campbell, Peter J
%A Tubio, Jose M C
%A Akdemir, Kadir C
%A Alvarez, Eva G
%A Baez-Ortega, Adrian
%A Beroukhim, Rameen
%A Boutros, Paul C
%A Bowtell, David D L
%A Brors, Benedikt
%A Burns, Kathleen H
%A Campbell, Peter J
%A Chan, Kin
%A Chen, Ken
%A Cortés-Ciriano, Isidro
%A Dueso-Barroso, Ana
%A Dunford, Andrew J
%A Edwards, Paul A
%A Estivill, Xavier
%A Etemadmoghadam, Dariush
%A Feuerbach, Lars
%A Fink, J Lynn
%A Frenkel-Morgenstern, Milana
%A Garsed, Dale W
%A Gerstein, Mark
%A Gordenin, Dmitry A
%A Haan, David
%A Haber, James E
%A Hess, Julian M
%A Hutter, Barbara
%A Imielinski, Marcin
%A Jones, David T W
%A Ju, Young Seok
%A Kazanov, Marat D
%A Klimczak, Leszek J
%A Koh, Youngil
%A Korbel, Jan O
%A Kumar, Kiran
%A Lee, Eunjung Alice
%A Lee, Jake June-Koo
%A Li, Yilong
%A Lynch, Andy G
%A Macintyre, Geoff
%A Markowetz, Florian
%A Martincorena, Iñigo
%A Martinez-Fundichely, Alexander
%A Meyerson, Matthew
%A Miyano, Satoru
%A Nakagawa, Hidewaki
%A Navarro, Fabio C P
%A Ossowski, Stephan
%A Park, Peter J
%A Pearson, John V
%A Puiggròs, Montserrat
%A Rippe, Karsten
%A Roberts, Nicola D
%A Roberts, Steven A
%A Rodriguez-Martin, Bernardo
%A Schumacher, Steven E
%A Scully, Ralph
%A Shackleton, Mark
%A Sidiropoulos, Nikos
%A Sieverling, Lina
%A Stewart, Chip
%A Sültmann, Holger
%A Torrents, David
%A Tubio, Jose M C
%A Villasante, Izar
%A Waddell, Nicola
%A Wala, Jeremiah A
%A Weischenfeldt, Joachim
%A Yang, Lixing
%A Yao, Xiaotong
%A Yoon, Sung-Soo
%A Zamora, Jorge
%A Zhang, Cheng-Zhong
%T Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.
%J Nature genetics
%V 52
%N 3
%@ 1546-1718
%C London
%I Macmillan Publishers Limited, part of Springer Nature
%M DKFZ-2020-00432
%P 306-319
%D 2020
%Z 2020 Mar;52(3):306-319
%X About half of all cancers have somatic integrations of retrotransposons. Here, to characterize their role in oncogenesis, we analyzed the patterns and mechanisms of somatic retrotransposition in 2,954 cancer genomes from 38 histological cancer subtypes within the framework of the Pan-Cancer Analysis of Whole Genomes (PCAWG) project. We identified 19,166 somatically acquired retrotransposition events, which affected 35
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:32024998
%R 10.1038/s41588-019-0562-0
%U https://inrepo02.dkfz.de/record/153735