%0 Journal Article
%A Anusruti, Ankita
%A Xuan, Yang
%A Gào, Xīn
%A Jansen, Eugène H J M
%A Laetsch, Dana Clarissa
%A Brenner, Hermann
%A Schöttker, Ben
%T Factors associated with high oxidative stress in patients with type 2 diabetes: a meta-analysis of two cohort studies.
%J BMJ Open Diabetes Research & Care
%V 8
%N 1
%@ 2052-4897
%C London
%I BMJ Publishing Group
%M DKFZ-2020-00461
%P e000933
%D 2020
%Z #EA:C070#LA:C070#
%X Our objective is to identify the potential factors associated with serum Diacron's reactive oxygen metabolites test (D-ROM) levels of patients with type 2 diabetes mellitus (T2DM) by conducting cross-sectional and longitudinal analyses in two large cohorts and further strengthening these results by performing a meta-analysis.Serum D-ROM concentrations were measured in 1045 and 1101 patients with T2DM from two independent cohort studies from Germany at baseline and repeatedly 3-4 years later. The cross-sectional and longitudinal associations of various potential determinants with D-ROM levels were assessed with a backwards selection algorithm in multivariable adjusted models.In the meta-analysis of the cross-sectional analysis, female sex, low education, obesity, smoking, high total cholesterol, hemoglobin A1c ≥7
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:32079612
%R 10.1136/bmjdrc-2019-000933
%U https://inrepo02.dkfz.de/record/153795