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@ARTICLE{Langer:153879,
      author       = {S. Langer and J. Horn and A. Kluttig and R. Mikolajczyk and
                      S. Karrasch and H. Schulz and H.-E. Wichmann and J.
                      Linseisen and L. Jaeschke and T. Pischon and J. Fricke and
                      T. Keil and W. Ahrens and K. Günther and O. Kuß and T.
                      Schikowski and B. Schmidt and K.-H. Jöckel and K. B.
                      Michels and C.-W. Franzke and H. Becher and A. Jagodzinski
                      and S. Castell and Y. Kemmling and W. Lieb and S. Waniek and
                      K. Wirkner and M. Löffler and R. Kaaks$^*$ and K. H.
                      Greiser$^*$ and K. Berger and N. Legath and C. Meinke-Franze
                      and S. Schipf and M. Leitzmann and H. Baurecht and K.
                      Weigl$^*$ and E. Amitay$^*$ and C. Gottschick},
      title        = {[{O}ccurrence of bronchial asthma and age at initial asthma
                      diagnosis-first results of the {G}erman {N}ational
                      {C}ohort].},
      journal      = {Bundesgesundheitsblatt, Gesundheitsforschung,
                      Gesundheitsschutz},
      volume       = {63},
      number       = {4},
      issn         = {1437-1588},
      address      = {Heidelberg},
      publisher    = {Springer},
      reportid     = {DKFZ-2020-00494},
      pages        = {397-403},
      year         = {2020},
      note         = {2020 Apr;63(4):397-403},
      abstract     = {Asthma is one of the most common chronic diseases in both
                      children and adults. Asthma first occurring in adulthood
                      (adult-onset asthma, AOA) is associated with poorer
                      prognosis compared to childhood-onset asthma (COA), which
                      urgently calls for more research in this area. The aim of
                      this work was to analyze the data on asthma collected in the
                      German National Cohort and compare it with the German Health
                      Interview and Examination Survey for Adults (DEGS), in
                      particular regarding AOA.Our analysis was based on the
                      dataset of the main questionnaire at mid-term of the German
                      National Cohort baseline examination, comprising 101,723
                      participants. Variables considered in the analyses were
                      self-reported diagnosis of asthma, age at first diagnosis,
                      asthma treatment in the past 12 months, age, and sex.In the
                      midterm dataset, $8.7\%$ of women and $7.0\%$ of men in the
                      German National Cohort reported that they had ever been
                      diagnosed with asthma. Approximately one third of
                      participants with asthma received their initial diagnosis
                      before their 18th birthday. COA affected $2.2\%$ of women
                      and $2.8\%$ of men, whereas AOA affected $6.5\%$ of women
                      and $4.2\%$ of men. During the previous 12 months, $33\%$
                      of COA cases and $60\%$ of AOA cases were medically
                      treated.The proportion of persons affected by asthma in the
                      German National Cohort, as well as observed patterns
                      regarding age and gender, corresponds to other data sources
                      such as DEGS. However, in our analysis, the proportion of
                      individuals with AOA was higher than described in the
                      literature. The increase in cumulative asthma diagnoses with
                      age is markedly steeper in younger participants, indicating
                      a rising trend over time.},
      cin          = {C020 / C070},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331 / I:(DE-He78)C070-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32125462},
      doi          = {10.1007/s00103-020-03105-y},
      url          = {https://inrepo02.dkfz.de/record/153879},
}