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@ARTICLE{Holtfreter:154101,
      author       = {B. Holtfreter and S. Samietz and K. Hertrampf and G. Aarabi
                      and D. Hagenfeld and T.-S. Kim and T. Kocher and B. Koos and
                      M. Schmitter and W. Ahrens and E. Alwers$^*$ and H. Becher
                      and K. Berger and H. Brenner$^*$ and A. Damms-Machado$^*$
                      and N. Ebert and B. Fischer and C.-W. Franzke and S.
                      Frölich and H. Greiser$^*$ and A. Gies$^*$ and K. Günther
                      and L. Hassan and W. Hoffmann and L. Jaeschke and T. Keil
                      and Y. Kemmling and G. Krause and L. Krist and N. Legath and
                      W. Lieb and M. Leitzmann and J. Linseisen and M. Loeffler
                      and C. Meinke-Franze and K. B. Michels and R. Mikolajczyk
                      and N. Obi and A. Peters and T. Pischon and S. Schipf and B.
                      Schmidt and H. Völzke and S. Waniek and C. Wigmann and K.
                      Wirkner and C. O. Schmidt and J. Kühnisch and S. Rupf},
      title        = {[{D}esign and quality control of the oral health status
                      examination in the {G}erman {N}ational {C}ohort ({GNC})].},
      journal      = {Bundesgesundheitsblatt, Gesundheitsforschung,
                      Gesundheitsschutz},
      volume       = {63},
      number       = {4},
      issn         = {1437-1588},
      address      = {Heidelberg},
      publisher    = {Springer},
      reportid     = {DKFZ-2020-00562},
      pages        = {426-438},
      year         = {2020},
      note         = {2020 Apr;63(4):426-438.},
      abstract     = {Caries and periodontitis are highly prevalent worldwide.
                      Because detailed data on these oral diseases were collected
                      within the framework of the German National Cohort (GNC),
                      associations between oral and systemic diseases and
                      conditions can be investigated.The study protocol for the
                      oral examination was designed to ensure a comprehensive
                      collection of dental findings by trained non-dental staff
                      within a limited examination time. At the mid-term of the
                      GNC baseline examination, a first quality evaluation was
                      performed to check the plausibility of results and to
                      propose measures to improve the data quality.A dental
                      interview, saliva sampling and oral diagnostics were
                      conducted. As part of the level‑1 examination, the number
                      of teeth and prostheses were recorded. As part of the
                      level‑2 examination, detailed periodontal, cariological
                      and functional aspects were examined. All examinations were
                      conducted by trained non-dental personnel. Parameters were
                      checked for plausibility and variable distributions were
                      descriptively analysed.Analyses included data of 57,967
                      interview participants, 56,913 level‑1 participants and
                      6295 level‑2 participants. Percentages of missing values
                      for individual clinical parameters assessed in level 1 and
                      level 2 ranged between 0.02 and $3.9\%.$ Results showed
                      a plausible distribution of the data; rarely, implausible
                      values were observed, e.g. for measurements of horizontal
                      and vertical overbite (overjet and overbite). Intra-class
                      correlation coefficients indicated differences in individual
                      parameters between regional clusters, study centres and
                      across different examiners.The results confirm the
                      feasibility of the study protocol by non-dental personnel
                      and its successful integration into the GNC's overall
                      assessment program. However, rigorous dental support of the
                      study centres is required for quality management.},
      cin          = {C070 / C020 / C120},
      ddc          = {610},
      cid          = {I:(DE-He78)C070-20160331 / I:(DE-He78)C020-20160331 /
                      I:(DE-He78)C120-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32166336},
      doi          = {10.1007/s00103-020-03107-w},
      url          = {https://inrepo02.dkfz.de/record/154101},
}