000154108 001__ 154108
000154108 005__ 20240229123056.0
000154108 0247_ $$2doi$$a10.1002/ijc.32977
000154108 0247_ $$2pmid$$apmid:32176325
000154108 0247_ $$2ISSN$$a0020-7136
000154108 0247_ $$2ISSN$$a1097-0215
000154108 0247_ $$2altmetric$$aaltmetric:77677550
000154108 037__ $$aDKFZ-2020-00569
000154108 041__ $$aeng
000154108 082__ $$a610
000154108 1001_ $$00000-0003-1049-6225$$aNaudin, Sabine$$b0
000154108 245__ $$aHealthy lifestyle and the risk of lymphoma in the EPIC study.
000154108 260__ $$aBognor Regis$$bWiley-Liss$$c2020
000154108 3367_ $$2DRIVER$$aarticle
000154108 3367_ $$2DataCite$$aOutput Types/Journal article
000154108 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1597734427_11199
000154108 3367_ $$2BibTeX$$aARTICLE
000154108 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000154108 3367_ $$00$$2EndNote$$aJournal Article
000154108 500__ $$a2020 Sep 15;147(6):1649-1656
000154108 520__ $$aLimited evidence exists on the role of modifiable lifestyle factors on the risk of lymphoma. In this work, the associations between adherence to healthy lifestyles and risks of Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) were evaluated in a large-scale European prospective cohort. Within the European Prospective Investigation into Cancer and Nutrition (EPIC), 2,999 incident lymphoma cases (132 HL and 2,746 NHL) were diagnosed among 453,808 participants after 15 years (median) of follow-up. The healthy lifestyle index (HLI) score combined information on smoking, alcohol intake, diet, physical activity and BMI, with large values of HLI expressing adherence to healthy behavior. Cox proportional hazards models were used to estimate lymphoma hazard ratios (HR) and 95% confidence interval (CI). Sensitivity analyses were conducted by excluding, in turn, each lifestyle factor from the HLI score. The HLI was inversely associated with HL, with HR for a 1-standard deviation (SD) increment in the score equal to 0.78 (95%CI: 0.66, 0.94). Sensitivity analyses showed that the association was mainly driven by smoking and marginally by diet. NHL risk was not associated with the HLI, with HRs for a 1-SD increment equal to 0.99 (0.95, 1.03), with no evidence for heterogeneity in the association across NHL subtypes. In the EPIC study, adherence to healthy lifestyles was not associated with overall lymphoma or NHL risk, while an inverse association was observed for HL, although this was largely attributable to smoking. These findings suggest a limited role of lifestyle factors in the etiology of lymphoma subtypes. This article is protected by copyright. All rights reserved.
000154108 536__ $$0G:(DE-HGF)POF3-313$$a313 - Cancer risk factors and prevention (POF3-313)$$cPOF3-313$$fPOF III$$x0
000154108 588__ $$aDataset connected to CrossRef, PubMed,
000154108 7001_ $$aSolans Margalef, Marta$$b1
000154108 7001_ $$00000-0002-7572-9715$$aSaberi Hosnijeh, Fatemeh$$b2
000154108 7001_ $$aNieters, Alexandra$$b3
000154108 7001_ $$00000-0002-9083-8960$$aKyrø, Cecilie$$b4
000154108 7001_ $$aTjønneland, Anne$$b5
000154108 7001_ $$aDahm, Christina C$$b6
000154108 7001_ $$aOvervad, Kim$$b7
000154108 7001_ $$aMahamat-Saleh, Yahya$$b8
000154108 7001_ $$00000-0003-4364-7173$$aBesson, Caroline$$b9
000154108 7001_ $$00000-0002-5956-5693$$aBoutron-Ruault, Marie-Christine$$b10
000154108 7001_ $$0P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe$$aKühn, Tilman$$b11$$udkfz
000154108 7001_ $$0P:(DE-He78)5323704270b6393dcea70186ffd86bca$$aCanzian, Federico$$b12$$udkfz
000154108 7001_ $$aSchulze, Matthias B$$b13
000154108 7001_ $$aPeppa, Eleni$$b14
000154108 7001_ $$aKarakatsani, Anna$$b15
000154108 7001_ $$aTrichopoulou, Antonia$$b16
000154108 7001_ $$00000-0001-5201-172X$$aSieri, Sabina$$b17
000154108 7001_ $$aMasala, Giovana$$b18
000154108 7001_ $$aPanico, Salvatore$$b19
000154108 7001_ $$aTumino, Rosario$$b20
000154108 7001_ $$00000-0001-8749-9737$$aRicceri, Fulvio$$b21
000154108 7001_ $$aChen, Sairah Lai Fa$$b22
000154108 7001_ $$aBarroso, Leila Luján$$b23
000154108 7001_ $$aHuerta, José María$$b24
000154108 7001_ $$aSánchez, Maria-Jose$$b25
000154108 7001_ $$aArdanaz, Eva$$b26
000154108 7001_ $$aMenéndez, Virginia$$b27
000154108 7001_ $$aAmiano Exezarreta, Pilar$$b28
000154108 7001_ $$aSpaeth, Florentin$$b29
000154108 7001_ $$aJerkeman, Mats$$b30
000154108 7001_ $$aJirstom, Karin$$b31
000154108 7001_ $$00000-0002-7733-8750$$aSchmidt, Julie A$$b32
000154108 7001_ $$aAune, Dagfinn$$b33
000154108 7001_ $$00000-0003-2237-0128$$aWeiderpass, Elisabete$$b34
000154108 7001_ $$aRiboli, Elio$$b35
000154108 7001_ $$aVermeulen, Roel$$b36
000154108 7001_ $$aCasabonne, Delphine$$b37
000154108 7001_ $$aGunter, Marc$$b38
000154108 7001_ $$00000-0002-0518-8714$$aBrennan, Paul$$b39
000154108 7001_ $$aFerrari, Pietro$$b40
000154108 773__ $$0PERI:(DE-600)1474822-8$$a10.1002/ijc.32977$$gp. ijc.32977$$n6$$p1649-1656$$tInternational journal of cancer$$v147$$x1097-0215$$y2020
000154108 909CO $$ooai:inrepo02.dkfz.de:154108$$pVDB
000154108 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe$$aDeutsches Krebsforschungszentrum$$b11$$kDKFZ
000154108 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)5323704270b6393dcea70186ffd86bca$$aDeutsches Krebsforschungszentrum$$b12$$kDKFZ
000154108 9131_ $$0G:(DE-HGF)POF3-313$$1G:(DE-HGF)POF3-310$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vCancer risk factors and prevention$$x0
000154108 9141_ $$y2020
000154108 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz
000154108 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000154108 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000154108 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000154108 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bINT J CANCER : 2017
000154108 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List
000154108 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index
000154108 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000154108 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000154108 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences
000154108 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews
000154108 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bINT J CANCER : 2017
000154108 9201_ $$0I:(DE-He78)C020-20160331$$kC020$$lC020 Epidemiologie von Krebs$$x0
000154108 9201_ $$0I:(DE-He78)C055-20160331$$kC055$$lC055 Genomische Epidemiologie$$x1
000154108 980__ $$ajournal
000154108 980__ $$aVDB
000154108 980__ $$aI:(DE-He78)C020-20160331
000154108 980__ $$aI:(DE-He78)C055-20160331
000154108 980__ $$aUNRESTRICTED