%0 Journal Article
%A Eyl, Ruth Elisa
%A Koch-Gallenkamp, Lena
%A Jansen, Lina
%A Walter, Viola
%A Carr, Prudence R
%A Hoffmeister, Michael
%A Chang-Claude, Jenny
%A Brenner, Hermann
%A Arndt, Volker
%T Physical activity and long-term quality of life among colorectal cancer survivors - a population-based prospective study.
%J Cancer Prevention Research
%V 13
%N 7
%@ 1940-6215
%C Philadelphia, Pa.
%I AACR
%M DKFZ-2020-00761
%P 611-622
%D 2020
%Z 2020 Jul;13(7):611-622#EA:C070#LA:C071#
%X Evidence suggests that physical activity(PA) is positively associated with health-related quality of life(QOL) in colorectal cancer(CRC) survivors. However, little is known regarding long-term effects of PA on QOL and if pre-diagnosis PA is associated with QOL in the years after diagnosis. Our study aimed to investigate the association of pre- and post-diagnosis PA with long-term QOL in CRC survivors. This study is based on a population-based cohort from Germany of 1781 newly diagnosed CRC survivors over a five-year period. Physical activity was assessed at diagnosis and at five-year follow up(5YFU). Quality of life was assessed by the EORTC Quality of Life Questionnaire-Core 30 at 5YFU. Multivariable linear regression was used to explore associations between pre- and post-diagnosis PA and QOL. No evidence of a positive association between higher levels of pre-diagnosis PA and better long-term QOL was found. Higher levels of pre-diagnosis work-related PA and vigorous PA were even associated with decreased QOL in domains such as cognitive (Beta(ß)= -2.52, 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:32253267
%R 10.1158/1940-6207.CAPR-19-0377
%U https://inrepo02.dkfz.de/record/154433