TY  - JOUR
AU  - Eyl, Ruth Elisa
AU  - Koch-Gallenkamp, Lena
AU  - Jansen, Lina
AU  - Walter, Viola
AU  - Carr, Prudence R
AU  - Hoffmeister, Michael
AU  - Chang-Claude, Jenny
AU  - Brenner, Hermann
AU  - Arndt, Volker
TI  - Physical activity and long-term quality of life among colorectal cancer survivors - a population-based prospective study.
JO  - Cancer Prevention Research
VL  - 13
IS  - 7
SN  - 1940-6215
CY  - Philadelphia, Pa.
PB  - AACR
M1  - DKFZ-2020-00761
SP  - 611-622
PY  - 2020
N1  - 2020 Jul;13(7):611-622#EA:C070#LA:C071#
AB  - Evidence suggests that physical activity(PA) is positively associated with health-related quality of life(QOL) in colorectal cancer(CRC) survivors. However, little is known regarding long-term effects of PA on QOL and if pre-diagnosis PA is associated with QOL in the years after diagnosis. Our study aimed to investigate the association of pre- and post-diagnosis PA with long-term QOL in CRC survivors. This study is based on a population-based cohort from Germany of 1781 newly diagnosed CRC survivors over a five-year period. Physical activity was assessed at diagnosis and at five-year follow up(5YFU). Quality of life was assessed by the EORTC Quality of Life Questionnaire-Core 30 at 5YFU. Multivariable linear regression was used to explore associations between pre- and post-diagnosis PA and QOL. No evidence of a positive association between higher levels of pre-diagnosis PA and better long-term QOL was found. Higher levels of pre-diagnosis work-related PA and vigorous PA were even associated with decreased QOL in domains such as cognitive (Beta(ß)= -2.52, 95
LB  - PUB:(DE-HGF)16
C6  - pmid:32253267
DO  - DOI:10.1158/1940-6207.CAPR-19-0377
UR  - https://inrepo02.dkfz.de/record/154433
ER  -