%0 Journal Article
%A Trares, Kira
%A Gào, Xīn
%A Perna, Laura
%A Rujescu, Dan
%A Stocker, Hannah
%A Möllers, Tobias
%A Beyreuther, Konrad
%A Brenner, Hermann
%A Schöttker, Ben
%T Associations of urinary 8-iso-prostaglandin F2α levels with all-cause dementia, Alzheimer's disease, and vascular dementia incidence: results from a prospective cohort study.
%J Alzheimer's and dementia
%V 16
%N 5
%@ 1552-5260
%C Amsterdam [u.a.]
%I Elsevier
%M DKFZ-2020-00789
%P 804-813
%D 2020
%Z 2020 May;16(5):804-813#EA:C070#LA:C070#
%X Prospective studies on a potential association of 8-iso-prostaglandin F2α (8-iso-PGF2α ) levels, a biomarker of lipid peroxidation, with dementia are limited.Multivariate Cox regression models were used to assess potential associations of urinary 8-iso-PGF2α levels with all-cause, Alzheimer's disease (AD), and vascular dementia (VD) incidence in 5853 older adults from a German, population-based cohort.Over 14 years of follow-up, 365 all-cause dementia cases including 127 VD and 109 AD cases were diagnosed. Participants in the top compared to the bottom 8-iso-PGF2α tertile had a 45
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:32281305
%R 10.1002/alz.12081
%U https://inrepo02.dkfz.de/record/154467