TY  - JOUR
AU  - Trares, Kira
AU  - Gào, Xīn
AU  - Perna, Laura
AU  - Rujescu, Dan
AU  - Stocker, Hannah
AU  - Möllers, Tobias
AU  - Beyreuther, Konrad
AU  - Brenner, Hermann
AU  - Schöttker, Ben
TI  - Associations of urinary 8-iso-prostaglandin F2α levels with all-cause dementia, Alzheimer's disease, and vascular dementia incidence: results from a prospective cohort study.
JO  - Alzheimer's and dementia
VL  - 16
IS  - 5
SN  - 1552-5260
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - DKFZ-2020-00789
SP  - 804-813
PY  - 2020
N1  - 2020 May;16(5):804-813#EA:C070#LA:C070#
AB  - Prospective studies on a potential association of 8-iso-prostaglandin F2α (8-iso-PGF2α ) levels, a biomarker of lipid peroxidation, with dementia are limited.Multivariate Cox regression models were used to assess potential associations of urinary 8-iso-PGF2α levels with all-cause, Alzheimer's disease (AD), and vascular dementia (VD) incidence in 5853 older adults from a German, population-based cohort.Over 14 years of follow-up, 365 all-cause dementia cases including 127 VD and 109 AD cases were diagnosed. Participants in the top compared to the bottom 8-iso-PGF2α tertile had a 45
LB  - PUB:(DE-HGF)16
C6  - pmid:32281305
DO  - DOI:10.1002/alz.12081
UR  - https://inrepo02.dkfz.de/record/154467
ER  -