% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Niedermaier:154657,
      author       = {T. Niedermaier$^*$ and E. Amitay$^*$ and A. Gies$^*$ and K.
                      Weigl$^*$ and M. Hoffmeister$^*$ and H. Brenner$^*$},
      title        = {{I}mpact of {I}nadequate {B}owel {C}leansing on
                      {C}olonoscopic {F}indings in {R}outine {S}creening
                      {P}ractice.},
      journal      = {Clinical and translational gastroenterology},
      volume       = {11},
      number       = {4},
      issn         = {2155-384X},
      address      = {London},
      publisher    = {Nature Publ. Group},
      reportid     = {DKFZ-2020-00918},
      pages        = {e00169},
      year         = {2020},
      note         = {#EA:C070#LA:C070#},
      abstract     = {Colonoscopy is an imperfect gold standard for detecting
                      colorectal neoplasms because some proportion of adenomas may
                      be missed, mainly small lesions. This proportion is expected
                      to be higher in case of inadequate bowel cleansing, which is
                      frequently seen in routine practice. We estimated the
                      proportions of neoplasms that are in principle detectable by
                      colonoscopy but might be missed in case of incomplete bowel
                      preparation.For 8,193 participants of screening colonoscopy
                      in South-Western Germany, recruited between 2005 and 2016,
                      the prevalence and numbers of different findings were
                      extracted from colonoscopy reports and compared according to
                      the reported bowel preparation quality.Bowel preparation
                      quality was reported as good, poor, or was unspecified in
                      $30.3\%,$ $11.1\%,$ and $58.6\%$ of colonoscopy records.
                      Reported prevalences of nonadvanced adenomas (NAAs) were
                      similar among participants with poor and unspecified bowel
                      preparation quality but substantially lower than among
                      participants with good bowel preparation (adjusted
                      prevalence rate ratio [RR] 0.86, $95\%$ confidence interval
                      [CI]: 0.77-0.96). The differences were observed for proximal
                      but not for distal NAAs (RRs 0.82, $95\%$ CI: 0.71-0.95 and
                      0.95, $95\%$ CI: 0.82-1.10).Our study suggests that a
                      significant proportion of NAAs located in the proximal colon
                      might be missed during colonoscopy if bowel cleansing is not
                      adequate. Major efforts should be made to further facilitate
                      and enhance high-quality bowel preparation in routine
                      screening practice.},
      cin          = {HD01 / C070 / C120},
      ddc          = {610},
      cid          = {I:(DE-He78)HD01-20160331 / I:(DE-He78)C070-20160331 /
                      I:(DE-He78)C120-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32352678},
      doi          = {10.14309/ctg.0000000000000169},
      url          = {https://inrepo02.dkfz.de/record/154657},
}