%0 Journal Article %A Schwingshackl, Lukas %A Zähringer, Jasmin %A Nitschke, Kai %A Torbahn, Gabriel %A Lohner, Szimonetta %A Kühn, Tilman %A Fontana, Luigi %A Veronese, Nicola %A Schmucker, Christine %A Meerpohl, Joerg J %T Impact of intermittent energy restriction on anthropometric outcomes and intermediate disease markers in patients with overweight and obesity: systematic review and meta-analyses. %J Critical reviews in food science and nutrition %V 61 %N 8 %@ 1549-7852 %C London %I Taylor and Francis %M DKFZ-2020-00960 %P 1293-1304 %D 2021 %Z 2021;61(8):1293-1304 %X This systematic review aims to investigate the effects of intermittent energy restriction (IER) on anthropometric outcomes and intermediate disease markers. A systematic literature search was conducted in three electronic databases. Randomized controlled trials (RCTs) were included if the intervention lasted ≥12 weeks and IER was compared with either continuous energy restriction (CER) or a usual diet. Random-effects meta-analysis was performed for eight outcomes. Certainty of evidence was assessed using GRADE. Seventeen RCTs with 1328 participants were included. IER in comparison to a usual diet may reduce body weight (mean difference [MD]: -4.83 kg, 95 %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:32363896 %R 10.1080/10408398.2020.1757616 %U https://inrepo02.dkfz.de/record/154702