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000154702 1001_ $$aSchwingshackl, Lukas$$b0
000154702 245__ $$aImpact of intermittent energy restriction on anthropometric outcomes and intermediate disease markers in patients with overweight and obesity: systematic review and meta-analyses.
000154702 260__ $$aLondon$$bTaylor and Francis$$c2021
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000154702 500__ $$a2021;61(8):1293-1304
000154702 520__ $$aThis systematic review aims to investigate the effects of intermittent energy restriction (IER) on anthropometric outcomes and intermediate disease markers. A systematic literature search was conducted in three electronic databases. Randomized controlled trials (RCTs) were included if the intervention lasted ≥12 weeks and IER was compared with either continuous energy restriction (CER) or a usual diet. Random-effects meta-analysis was performed for eight outcomes. Certainty of evidence was assessed using GRADE. Seventeen RCTs with 1328 participants were included. IER in comparison to a usual diet may reduce body weight (mean difference [MD]: -4.83 kg, 95%-CI: -5.46, -4.21; n = 6 RCTs), waist circumference (MD: -1.73 cm, 95%-CI: -3.69, 0.24; n = 2), fat mass (MD: -2.54 kg, 95%-CI: -3.78, -1.31; n = 6), triacylglycerols (MD: -0.20 mmol/L, 95%-CI: -0.38, -0.03; n = 5) and systolic blood pressure (MD: -6.11 mmHg, 95%-CI: -9.59, -2.64; n = 5). No effects were observed for LDL-cholesterol, fasting glucose, and glycosylated-hemoglobin. Both, IER and CER have similar effect on body weight (MD: -0.55 kg, 95%-CI: -1.01, -0.09; n = 13), and fat mass (MD: -0.66 kg, 95%-CI: -1.14, -0.19; n = 10), and all other outcomes. In conclusion, IER improves anthropometric outcomes and intermediate disease markers when compared to a usual diet. The effects of IER on weight loss are similar to weight loss achieved by CER.
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000154702 7001_ $$aZähringer, Jasmin$$b1
000154702 7001_ $$aNitschke, Kai$$b2
000154702 7001_ $$aTorbahn, Gabriel$$b3
000154702 7001_ $$aLohner, Szimonetta$$b4
000154702 7001_ $$0P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe$$aKühn, Tilman$$b5$$udkfz
000154702 7001_ $$aFontana, Luigi$$b6
000154702 7001_ $$aVeronese, Nicola$$b7
000154702 7001_ $$aSchmucker, Christine$$b8
000154702 7001_ $$aMeerpohl, Joerg J$$b9
000154702 773__ $$0PERI:(DE-600)2028517-6$$a10.1080/10408398.2020.1757616$$gp. 1 - 12$$n8$$p1293-1304$$tCritical reviews in food science and nutrition$$v61$$x1549-7852$$y2021
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