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041 | _ | _ | |a eng |
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100 | 1 | _ | |a Schwingshackl, Lukas |b 0 |
245 | _ | _ | |a Impact of intermittent energy restriction on anthropometric outcomes and intermediate disease markers in patients with overweight and obesity: systematic review and meta-analyses. |
260 | _ | _ | |a London |c 2021 |b Taylor and Francis |
336 | 7 | _ | |a article |2 DRIVER |
336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1617968781_30754 |2 PUB:(DE-HGF) |x Review Article |
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336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
500 | _ | _ | |a 2021;61(8):1293-1304 |
520 | _ | _ | |a This systematic review aims to investigate the effects of intermittent energy restriction (IER) on anthropometric outcomes and intermediate disease markers. A systematic literature search was conducted in three electronic databases. Randomized controlled trials (RCTs) were included if the intervention lasted ≥12 weeks and IER was compared with either continuous energy restriction (CER) or a usual diet. Random-effects meta-analysis was performed for eight outcomes. Certainty of evidence was assessed using GRADE. Seventeen RCTs with 1328 participants were included. IER in comparison to a usual diet may reduce body weight (mean difference [MD]: -4.83 kg, 95%-CI: -5.46, -4.21; n = 6 RCTs), waist circumference (MD: -1.73 cm, 95%-CI: -3.69, 0.24; n = 2), fat mass (MD: -2.54 kg, 95%-CI: -3.78, -1.31; n = 6), triacylglycerols (MD: -0.20 mmol/L, 95%-CI: -0.38, -0.03; n = 5) and systolic blood pressure (MD: -6.11 mmHg, 95%-CI: -9.59, -2.64; n = 5). No effects were observed for LDL-cholesterol, fasting glucose, and glycosylated-hemoglobin. Both, IER and CER have similar effect on body weight (MD: -0.55 kg, 95%-CI: -1.01, -0.09; n = 13), and fat mass (MD: -0.66 kg, 95%-CI: -1.14, -0.19; n = 10), and all other outcomes. In conclusion, IER improves anthropometric outcomes and intermediate disease markers when compared to a usual diet. The effects of IER on weight loss are similar to weight loss achieved by CER. |
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700 | 1 | _ | |a Zähringer, Jasmin |b 1 |
700 | 1 | _ | |a Nitschke, Kai |b 2 |
700 | 1 | _ | |a Torbahn, Gabriel |b 3 |
700 | 1 | _ | |a Lohner, Szimonetta |b 4 |
700 | 1 | _ | |a Kühn, Tilman |0 P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe |b 5 |u dkfz |
700 | 1 | _ | |a Fontana, Luigi |b 6 |
700 | 1 | _ | |a Veronese, Nicola |b 7 |
700 | 1 | _ | |a Schmucker, Christine |b 8 |
700 | 1 | _ | |a Meerpohl, Joerg J |b 9 |
773 | _ | _ | |a 10.1080/10408398.2020.1757616 |g p. 1 - 12 |0 PERI:(DE-600)2028517-6 |n 8 |p 1293-1304 |t Critical reviews in food science and nutrition |v 61 |y 2021 |x 1549-7852 |
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