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001 | 154791 | ||
005 | 20240229123112.0 | ||
024 | 7 | _ | |a 10.1038/s41408-020-0323-4 |2 doi |
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100 | 1 | _ | |a Pulte, Dianne |0 P:(DE-HGF)0 |b 0 |e First author |
245 | _ | _ | |a Changes in long term survival after diagnosis with common hematologic malignancies in the early 21st century. |
260 | _ | _ | |a London [u.a.] |c 2020 |b Nature Publishing Group |
336 | 7 | _ | |a article |2 DRIVER |
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336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1600853209_25390 |2 PUB:(DE-HGF) |
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520 | _ | _ | |a Five-year survival has increased for many hematologic malignancies in the 21st century. However, whether this has translated into greater long-term survival is unknown. Here, we examine 10- and 20-year survival for patients with multiple myeloma (MM), acute lymphoblastic leukemia (ALL), acute myeloblastic leukemia (AML), chronic lymphoid leukemia (CLL), chronic myeloid leukemia (CML), non-Hodgkin lymphoma (NHL), and Hodgkin lymphoma (HL). Data were extracted from the Surveillance, Epidemiology, and End Results-9 database. Patients age 15+ with the above malignancies were included. The newly developed boomerang method was used to examine 10- and 20-year relative survival (RS) for patients in 2002-2006 and 2012-16. Ten and 20-year RS increased for each malignancy examined, with increases ranging from +4.4% units for 20-year RS for AML to +23.1% units for 10-year RS for CML. Ten year RS was >50% in 2012-16 for patients with CLL, CML, HL, NHL, and DLBCL, at 77.1%, 62.1%, 63.9%, 64.5%, and 63.0%, respectively. Survival dropped between 10 and 20 years after diagnosis for most malignancies. Long-term survival is increasing for common hematologic malignancies, but late mortality is an ongoing issue. Further study of long-term outcomes in curable malignancies to determine the reason for these later decreases in survival is indicated. |
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700 | 1 | _ | |a Jansen, Lina |0 P:(DE-He78)bbfe0ebad1e3b608bca2b49d4f86bd09 |b 1 |
700 | 1 | _ | |a Brenner, Hermann |0 P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2 |b 2 |e Last author |
773 | _ | _ | |a 10.1038/s41408-020-0323-4 |g Vol. 10, no. 5, p. 56 |0 PERI:(DE-600)2600560-8 |n 5 |p 56 |t Blood cancer journal |v 10 |y 2020 |x 2044-5385 |
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