TY - JOUR
AU - Ali Khan, Uzair
AU - Fallah, Mahdi
AU - Tian, Yu
AU - Sundquist, Kristina
AU - Sundquist, Jan
AU - Brenner, Hermann
AU - Kharazmi, Elhamalsadat
TI - Personal History of Diabetes as Important as Family History of Colorectal Cancer for Risk of Colorectal Cancer: A Nationwide Cohort Study.
JO - The American journal of gastroenterology
VL - 115
IS - 7
SN - 0002-9270
CY - Alphen aan den Rijn, The Netherlands
PB - Wolters Kluwer Health, Inc.
M1 - DKFZ-2020-01175
SP - 1103-1109
PY - 2020
N1 - #EA:C120#LA:C120#
AB - Diabetes mellitus (DM) and colorectal cancer (CRC) share some risk factors, including lifestyle and metabolic disturbances. We aimed to provide in-depth information on the association of CRC risk, especially early-onset CRC, with DM, family history of CRC, and age at DM diagnosis.A nationwide cohort study was conducted using Swedish family cancer data sets, inpatient, and outpatient registers (follow-up: 1964-2015), including all individuals born after 1931 and their parents (12,614,256 individuals; 559,375 diabetic patients; 162,226 CRC patients).DM diagnosis before the age of 50 years was associated with a 1.9-fold increased risk of CRC before the age of 50 years (95
LB - PUB:(DE-HGF)16
C6 - pmid:32618661
DO - DOI:10.14309/ajg.0000000000000669
UR - https://inrepo02.dkfz.de/record/156858
ER -