%0 Journal Article
%A Yammine, Sahar
%A Huybrechts, Inge
%A Biessy, Carine
%A Dossus, Laure
%A Aglago, Elom K
%A Naudin, Sabine
%A Ferrari, Pietro
%A Weiderpass, Elisabete
%A Tjonneland, Anne
%A Hansen, Louise
%A Overvad, Kim
%A Romana Mancini, Francesca
%A Boutron-Ruault, Marie-Christine
%A Kvaskoff, Marina
%A Turzanski-Fortner, Renée
%A Kaaks, Rudolf
%A Schulze, Matthias B
%A Boing, Heiner
%A Trichopoulou, Antonia
%A Karakatsani, Anna
%A La Vecchia, Carlo
%A Benetou, Vassiliki
%A Masala, Giovanna
%A Krogh, Vittorio
%A Mattiello, Amalia
%A Macciotta, Alessandra
%A Gram, Inger T
%A Skeie, Guri
%A Quiros Garcia, Jose Ramon
%A Agudo, Antonio
%A Sanchez-Perez, Maria-Jose
%A Chirlaque, Maria-Dolores
%A Ardanaz, Eva
%A Gil, Leire
%A Sartor, Hanna
%A Drake, Isabel
%A Idahl, Annika
%A Lundin, Eva A
%A Aune, Dagfinn
%A Ward, Heather A
%A Merritt, Melissa A
%A Allen, Naomi E
%A Gunter, Marc J
%A Chajes, Veronique
%T Dietary and circulating fatty acids and ovarian cancer risk in the European Prospective Investigation into Cancer and Nutrition.
%J Cancer epidemiology, biomarkers & prevention
%V 29
%N 9
%@ 1538-7755
%C Philadelphia, Pa.
%I AACR
%M DKFZ-2020-01176
%P 1739-1749
%D 2020
%Z 2020 Sep;29(9):1739-1749
%X Fatty acids impact obesity, estrogens and inflammation, risk factors for ovarian cancer. Few epidemiological studies have investigated the association of fatty acids with ovarian cancer.Within the European Prospective Investigation into Cancer and nutrition, 1,486 incident ovarian cancer cases were identified. Cox Proportional Hazard models with adjustment for ovarian cancer risk factors were used to estimate hazard ratios of ovarian cancer across quintiles of intake of fatty acids. False discovery rate was computed to control for multiple testing. Multivariable conditional logistic regression models were used to estimate odds ratios of ovarian cancer across tertiles of plasma fatty acids among 633 cases and two matched controls in a nested case-control analysis.A positive association was found between ovarian cancer and intake of industrial trans elaidic acid (Hazard Ratio comparing 5th with 1st quintileQ5-Q1=1.29; 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:32616494
%R 10.1158/1055-9965.EPI-19-1477
%U https://inrepo02.dkfz.de/record/156859