000156899 001__ 156899
000156899 005__ 20240229123120.0
000156899 0247_ $$2doi$$a10.1002/cam4.3197
000156899 0247_ $$2pmid$$apmid:32524704
000156899 0247_ $$2altmetric$$aaltmetric:84029668
000156899 037__ $$aDKFZ-2020-01206
000156899 041__ $$aeng
000156899 082__ $$a610
000156899 1001_ $$aAdam, Salome$$b0
000156899 245__ $$aHealth-related quality of life in long-term prostate cancer survivors after nerve-sparing and non-nerve-sparing radical prostatectomy-Results from the multiregional PROCAS study.
000156899 260__ $$aHoboken, NJ$$bWiley$$c2020
000156899 3367_ $$2DRIVER$$aarticle
000156899 3367_ $$2DataCite$$aOutput Types/Journal article
000156899 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1636021321_8518
000156899 3367_ $$2BibTeX$$aARTICLE
000156899 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000156899 3367_ $$00$$2EndNote$$aJournal Article
000156899 500__ $$a2020 Aug;9(15):5416-5424#LA:C071#
000156899 520__ $$aNerve-sparing (NS) surgery was developed to improve postoperative sexual and potentially urological outcomes after radical prostatectomy (RP). However, it is largely unknown how NSRP affects health-related quality of life (HRQoL) including urinary and sexual outcomes in prostate cancer (PC) survivors 5-10 years after diagnosis in comparison with Non-NSRP.The study population included 382 stage pT2-T3N0M0 PC survivors 5-10 years post diagnosis, who were identified from the multiregional Prostate Cancer Survivorship in Switzerland (PROCAS) study. Briefly, in 2017/2018, PC survivors were identified via six population-based cancer registries based in both German- and French-speaking Switzerland. HRQoL and PC-specific symptom burden was assessed using the EORTC QLQ-C30 and EORTC QLQ-PR25 questionnaires. Differences in HRQoL outcomes between survivors treated with NSRP (uni- & bilateral) and Non-NSRP were analyzed with multivariable linear regression adjusted for age, years since diagnosis, cancer stage, comorbidities at diagnosis, and further therapies, if appropriate. Multiple imputation was performed to minimize the bias due to missing data.Five to ten years after diagnosis, PC survivors treated with NSRP and Non-NSRP reported similar symptom burden and comparable HRQoL function scores. The only significant differences were reported for sexual activity, whereas PC survivors who underwent NSRP reported statistically significant (P = .031) higher sexual activity than those on Non-NSRP. NSRP and Non-NSRP reported similar scores for urinary symptoms and all other HRQoL outcomes.Our results support nerve-sparing techniques as an option to improve postoperative sexual, but not urinary outcomes after RP in long-term PC survivors.
000156899 536__ $$0G:(DE-HGF)POF3-313$$a313 - Cancer risk factors and prevention (POF3-313)$$cPOF3-313$$fPOF III$$x0
000156899 588__ $$aDataset connected to CrossRef, PubMed,
000156899 7001_ $$aMartin-Diener, Eva$$b1
000156899 7001_ $$aCamey, Bertrand$$b2
000156899 7001_ $$aEgger Hayoz, Céline$$b3
000156899 7001_ $$aKonzelmann, Isabelle$$b4
000156899 7001_ $$aMohsen Mousavi, Seyed$$b5
000156899 7001_ $$aHerrmann, Christian$$b6
000156899 7001_ $$aRohrmann, Sabine$$b7
000156899 7001_ $$aWanner, Miriam$$b8
000156899 7001_ $$aStaehelin, Katharina$$b9
000156899 7001_ $$aStrebel, Räto T$$b10
000156899 7001_ $$aRandazzo, Marco$$b11
000156899 7001_ $$aJohn, Hubert$$b12
000156899 7001_ $$aSchmid, Hans-Peter$$b13
000156899 7001_ $$0P:(DE-He78)d023fdf423d87ee6c710e34dd7581fa0$$aArndt, Volker$$b14$$eLast author$$udkfz
000156899 773__ $$0PERI:(DE-600)2659751-2$$a10.1002/cam4.3197$$gp. cam4.3197$$n15$$p5416-5424$$tCancer medicine$$v9$$x2045-7634$$y2020
000156899 909CO $$ooai:inrepo02.dkfz.de:156899$$pVDB
000156899 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)d023fdf423d87ee6c710e34dd7581fa0$$aDeutsches Krebsforschungszentrum$$b14$$kDKFZ
000156899 9131_ $$0G:(DE-HGF)POF3-313$$1G:(DE-HGF)POF3-310$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vCancer risk factors and prevention$$x0
000156899 9141_ $$y2020
000156899 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bCANCER MED-US : 2018$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0320$$2StatID$$aDBCoverage$$bPubMed Central$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Peer review$$d2020-01-09
000156899 915__ $$0LIC:(DE-HGF)CCBYNV$$2V:(DE-HGF)$$aCreative Commons Attribution CC BY (No Version)$$bDOAJ$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$f2020-01-09
000156899 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2020-01-09
000156899 9202_ $$0I:(DE-He78)C070-20160331$$kC070$$lC070 Klinische Epidemiologie und Alternf.$$x0
000156899 9201_ $$0I:(DE-He78)C071-20160331$$kC071$$lC071 Cancer Survivorship$$x0
000156899 980__ $$ajournal
000156899 980__ $$aVDB
000156899 980__ $$aI:(DE-He78)C071-20160331
000156899 980__ $$aUNRESTRICTED