TY  - JOUR
AU  - Eyl, Ruth Elisa
AU  - Thong, Melissa S Y
AU  - Carr, Prudence R
AU  - Jansen, Lina
AU  - Koch-Gallenkamp, Lena
AU  - Hoffmeister, Michael
AU  - Chang-Claude, Jenny
AU  - Brenner, Hermann
AU  - Arndt, Volker
TI  - Physical activity and long-term fatigue among colorectal cancer survivors - a population-based prospective study.
JO  - BMC cancer
VL  - 20
IS  - 1
SN  - 1471-2407
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2020-01376
SP  - 438
PY  - 2020
N1  - #EA:C070#LA:C071#
AB  - Evidence suggests that physical activity (PA) is beneficial for reducing fatigue in colorectal cancer (CRC) survivors. However, little is known regarding long-term effects of PA on fatigue and whether pre-diagnosis PA is associated with less fatigue in the years after diagnosis. Our study aimed to investigate the association of pre- and post-diagnosis PA with long-term fatigue in CRC survivors.This study used a German population-based cohort of 1781 individuals, diagnosed with CRC in 2003-2014, and alive at five-year follow-up (5YFU). Physical activity was assessed at diagnosis and at 5YFU. Fatigue was assessed by the Fatigue Assessment Questionnaire and the EORTC Quality of Life Questionnaire-Core 30 fatigue subscale at 5YFU. Multivariable linear regression was used to explore associations between pre- and post-diagnosis PA and fatigue at 5YFU.No evidence was found that pre-diagnosis PA was associated with less fatigue in long-term CRC survivors. Pre-diagnosis work-related PA and vigorous PA were even associated with higher levels of physical (Beta (ß) = 2.52, 95
LB  - PUB:(DE-HGF)16
C6  - pmid:32423448
C2  - pmc:PMC7236466
DO  - DOI:10.1186/s12885-020-06918-x
UR  - https://inrepo02.dkfz.de/record/157085
ER  -