% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{TurzanskiFortner:157337,
      author       = {R. Turzanski-Fortner$^*$ and M. S. Rice and S. F. Knutsen
                      and M. J. Orlich and K. Visvanathan and A. V. Patel and M.
                      M. Gaudet and A. Tjonneland and M. Kvaskoff and R. Kaaks$^*$
                      and A. Trichopoulou and V. Pala and N. C. Onland-Moret and
                      I. T. Gram and P. Amiano and A. Idahl and N. E. Allen and E.
                      Weiderpass and J. N. Poynter and K. Robien and G. G. Giles
                      and R. L. Milne and V. W. Setiawan and M. A. Merritt and P.
                      A. van den Brandt and A. Zeleniuch-Jacquotte and A. A.
                      Arslan and K. M. O'Brien and D. P. Sandler and A. Wolk and
                      N. Håkansson and H. R. Harris and B. Trabert and N.
                      Wentzensen and S. S. Tworoger and L. J. Schouten},
      title        = {{O}varian cancer risk factor associations by primary
                      anatomic site: the {O}varian {C}ancer {C}ohort
                      {C}onsortium.},
      journal      = {Cancer epidemiology, biomarkers $\&$ prevention},
      volume       = {29},
      number       = {10},
      issn         = {1538-7755},
      address      = {Philadelphia, Pa.},
      publisher    = {AACR},
      reportid     = {DKFZ-2020-01566},
      pages        = {2010-2018},
      year         = {2020},
      note         = {2020 Oct;29(10):2010-2018#EA:C020#},
      abstract     = {Epithelial ovarian, fallopian tube, and primary peritoneal
                      cancer have shared developmental pathways. Few studies have
                      prospectively examined heterogeneity in risk factor
                      associations across these three anatomic sites.We identified
                      3,738 ovarian, 337 peritoneal, and 176 fallopian tube
                      incident cancer cases in 891,731 women from 15 prospective
                      cohorts in the Ovarian Cancer Cohort Consortium.
                      Associations between 18 putative risk factors and risk of
                      ovarian, peritoneal, and fallopian tube cancer, overall and
                      for serous and high-grade serous tumors, were evaluated
                      using competing risks Cox proportional hazards regression.
                      Heterogeneity was assessed by likelihood ratio tests.Most
                      associations did not vary by tumor site (phet≥0.05).
                      Associations between first pregnancy (phet=0.04), tubal
                      ligation (phet=0.01) and early-adult (age 18-21 years) body
                      mass index (BMI) (phet=0.02) and risk differed between
                      ovarian and peritoneal cancers. The association between
                      early adult BMI and risk further differed between peritoneal
                      and fallopian tube cancer (phet=0.03). First pregnancy and
                      tubal ligation were inversely associated with ovarian, but
                      not peritoneal, cancer. Higher early-adult BMI was
                      associated with higher risk of peritoneal, but not ovarian
                      or fallopian tube, cancer. Patterns were generally similar
                      when restricted to serous and high-grade serous
                      cases.Ovarian, fallopian tube, and primary peritoneal
                      cancers appear to have both shared and distinct etiologic
                      pathways, although most risk factors appear to have similar
                      associations by anatomic site.Further studies on the
                      mechanisms underlying the differences in risk profiles may
                      provide insights regarding the developmental origins of
                      tumors arising in the peritoneal cavity and inform
                      prevention efforts.},
      cin          = {C020},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331},
      pnm          = {312 - Functional and structural genomics (POF3-312)},
      pid          = {G:(DE-HGF)POF3-312},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32732252},
      doi          = {10.1158/1055-9965.EPI-20-0354},
      url          = {https://inrepo02.dkfz.de/record/157337},
}