%0 Journal Article
%A Scherer, Dominique
%A Deutelmoser, Heike
%A Balavarca, Yesilda
%A Toth, Reka
%A Habermann, Nina
%A Buck, Katharina
%A Kap, Elisabeth Johanna
%A Botma, Akke
%A Seibold, Petra
%A Jansen, Lina
%A Lorenzo Bermejo, Justo
%A Weigl, Korbinian
%A Benner, Axel
%A Hoffmeister, Michael
%A Ulrich, Alexis
%A Brenner, Hermann
%A Burwinkel, Barbara
%A Chang-Claude, Jenny
%A Ulrich, Cornelia M
%T Polymorphisms in the Angiogenesis-Related Genes EFNB2, MMP2 and JAG1 Are Associated with Survival of Colorectal Cancer Patients.
%J International journal of molecular sciences
%V 21
%N 15
%@ 1422-0067
%C Basel
%I Molecular Diversity Preservation International
%M DKFZ-2020-01606
%P 5395
%D 2020
%Z #EA:C120#
%X An individual's inherited genetic variation may contribute to the 'angiogenic switch', which is essential for blood supply and tumor growth of microscopic and macroscopic tumors. Polymorphisms in angiogenesis-related genes potentially predispose to colorectal cancer (CRC) or affect the survival of CRC patients. We investigated the association of 392 single nucleotide polymorphisms (SNPs) in 33 angiogenesis-related genes with CRC risk and survival of CRC patients in 1754 CRC cases and 1781 healthy controls within DACHS (Darmkrebs: Chancen der Verhütung durch Screening), a German population-based case-control study. Odds ratios and 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:32751332
%R 10.3390/ijms21155395
%U https://inrepo02.dkfz.de/record/157411