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@ARTICLE{Jakab:157521,
      author       = {M. V. Jakab$^*$ and H. Augustin$^*$},
      title        = {{U}nderstanding angiodiversity: insights from single cell
                      biology.},
      journal      = {Development},
      volume       = {147},
      number       = {15},
      issn         = {1477-9129},
      address      = {Cambridge},
      publisher    = {The Company of Biologists},
      reportid     = {DKFZ-2020-01677},
      pages        = {dev146621 -},
      year         = {2020},
      note         = {#EA:A190#LA:A190#DKFZ-ZMBH Alliance},
      abstract     = {Blood vessels have long been considered as passive conduits
                      for delivering blood. However, in recent years, cells of the
                      vessel wall (endothelial cells, smooth muscle cells and
                      pericytes) have emerged as active, highly dynamic components
                      that orchestrate crosstalk between the circulation and
                      organs. Encompassing the whole body and being specialized to
                      the needs of distinct organs, it is not surprising that
                      vessel lining cells come in different flavours. There is
                      calibre-specific specialization (arteries, arterioles,
                      capillaries, venules, veins), but also organ-specific
                      heterogeneity in different microvascular beds (continuous,
                      discontinuous, sinusoidal). Recent technical advances in the
                      field of single cell biology have enabled the profiling of
                      thousands of single cells and, hence, have allowed for the
                      molecular dissection of such angiodiversity, yielding a
                      hitherto unparalleled level of spatial and functional
                      resolution. Here, we review how these approaches have
                      contributed to our understanding of angiodiversity.},
      subtyp        = {Review Article},
      cin          = {A190 / HD01},
      ddc          = {570},
      cid          = {I:(DE-He78)A190-20160331 / I:(DE-He78)HD01-20160331},
      pnm          = {321 - Basic Concepts (POF3-321)},
      pid          = {G:(DE-HGF)POF3-321},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32792338},
      doi          = {10.1242/dev.146621},
      url          = {https://inrepo02.dkfz.de/record/157521},
}