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| 024 | 7 | _ | |a 10.1016/j.euo.2020.08.004 |2 doi |
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| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Darr, Christopher |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a Three-dimensional Magnetic Resonance Imaging-based Printed Models of Prostate Anatomy and Targeted Biopsy-proven Index Tumor to Facilitate Patient-tailored Radical Prostatectomy-A Feasibility Study. |
| 260 | _ | _ | |a Amsterdam |c 2022 |b Elsevier |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1654249123_3574 |2 PUB:(DE-HGF) |
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| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a Volume 5, Issue 3, June 2022, Pages 357-361 |
| 520 | _ | _ | |a In this prospective single-center feasibility study, we demonstrate that the use of three-dimensional (3D)-printed prostate models support nerve-sparing radical prostatectomy (RP) and intraoperative frozen sectioning (IFS) in ten men suffering from intermediate- and high-risk prostate cancer (PC), of whom seven harbored pT3 disease. Patient-specific 3D resin models were printed based on preoperative multiparametric magnetic resonance imaging (mpMRI) to provide an exact 3D impression of significant tumor lesions. RP and IFS were planned in a patient-tailored fashion. The 36-region Prostate Imaging Reporting and Data System (PI-RADS) v2.0 scheme was used to compare the MRI/3D print with whole-mount histopathology. In all cases, localization of the index lesion was correctly displayed by MRI and the 3D model. Localization of significant PC lesions correlated significantly (Pearson`s correlation coefficient of 0.88; p < 0.001). In addition, a significant correlation of the width, length, and volume of the tumor and prostate gland, derived from the printed model and histopathology, was found, using Pearson's correlation analyses and Bland-Altman plots. In conclusion, 3D-printed prostate models correlate well with final pathology and can be used to tailor RP. PATIENT SUMMARY: The use of three-dimensional (3D)-printed prostate models based on preoperative magnetic resonance imaging (MRI) may improve prostatectomy outcome. This study confirmed the accuracy of 3D-printed prostates compared with pathology from radical prostatectomy specimens. Thus, MRI-derived 3D-printed prostate models can assist in prostate cancer surgery. |
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| 700 | 1 | _ | |a Finis, Friederike |0 P:(DE-HGF)0 |b 1 |
| 700 | 1 | _ | |a Wiesenfarth, Manuel |0 P:(DE-He78)1042737c83ba70ec508bdd99f0096864 |b 2 |
| 700 | 1 | _ | |a Giganti, Francesco |b 3 |
| 700 | 1 | _ | |a Tschirdewahn, Stephan |0 P:(DE-HGF)0 |b 4 |
| 700 | 1 | _ | |a Krafft, Ulrich |0 P:(DE-HGF)0 |b 5 |
| 700 | 1 | _ | |a Kesch, Claudia |0 P:(DE-HGF)0 |b 6 |
| 700 | 1 | _ | |a Bonekamp, David |0 P:(DE-He78)ea098e4d78abeb63afaf8c25ec6d6d93 |b 7 |
| 700 | 1 | _ | |a Forsting, Michael |0 P:(DE-HGF)0 |b 8 |
| 700 | 1 | _ | |a Wetter, Axel |0 P:(DE-HGF)0 |b 9 |
| 700 | 1 | _ | |a Reis, Henning |0 P:(DE-HGF)0 |b 10 |
| 700 | 1 | _ | |a Hadaschik, Boris A |0 P:(DE-HGF)0 |b 11 |
| 700 | 1 | _ | |a Haubold, Johannes |0 P:(DE-HGF)0 |b 12 |
| 700 | 1 | _ | |a Radtke, Jan Philipp |0 P:(DE-He78)79897f8897ff77676549d9895258a0f2 |b 13 |e Last author |
| 773 | _ | _ | |a 10.1016/j.euo.2020.08.004 |g p. S2588931120301280 |0 PERI:(DE-600)2945338-0 |n 3 |p 357-361 |t European urology oncology |v 5 |y 2022 |x 2588-9311 |
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