TY  - JOUR
AU  - Schmidt, Martina
AU  - Hermann, Silke
AU  - Arndt, Volker
AU  - Steindorf, Karen
TI  - Prevalence and severity of long-term physical, emotional, and cognitive fatigue across 15 different cancer entities.
JO  - Cancer medicine
VL  - 9
IS  - 21
SN  - 2045-7634
CY  - Hoboken, NJ
PB  - Wiley
M1  - DKFZ-2020-01823
SP  - 8053-8061
PY  - 2020
N1  - #EA:C110#LA:C110# 2020 Nov;9(21):8053-8061
AB  - Fatigue prevalence and severity have been assessed in a variety of studies, yet, not in a standardized way, and predominantly in breast cancer patients. Systematic, comparative investigations across a broad range of cancer entities are lacking.The FiX study systematically enrolled 2244 cancer patients across 15 entities approximately 2 years after diagnosis. Fatigue was assessed with the multidimensional EORTC QLQ-FA12 questionnaire. Physical, emotional, cognitive, and total fatigue were compared across entities and with normative values of the general population. Differences in patients' characteristics and cancer therapy between entities were taken into account using analyses of covariance models.Across all entities, mean physical fatigue levels were significantly higher than age- and sex-matched means of the general population for all cancer entities (all Bonferroni-Holm adjusted P < .01). For most entities also emotional and cognitive fatigue levels were significantly higher than normative values. Age- and sex-standardized physical fatigue prevalence ranged from 31.8
LB  - PUB:(DE-HGF)16
C6  - pmid:32893501
DO  - DOI:10.1002/cam4.3413
UR  - https://inrepo02.dkfz.de/record/163032
ER  -