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@ARTICLE{Taeubert:163182,
      author       = {L. Taeubert$^*$ and Y. Berker$^*$ and B.
                      Beuthien-Baumann$^*$ and A. L. Hoffmann and E. G. C.
                      Troost$^*$ and M. Kachelriess$^*$ and C. Gillmann$^*$},
      title        = {{CT}-based attenuation correction of whole-body
                      radiotherapy treatment positioning devices in {PET}/{MRI}
                      hybrid imaging.},
      journal      = {Physics in medicine and biology},
      volume       = {65},
      number       = {23},
      issn         = {1361-6560},
      address      = {Bristol},
      publisher    = {IOP Publ.},
      reportid     = {DKFZ-2020-01885},
      pages        = {23NT02},
      year         = {2020},
      note         = {#EA:E040#LA:#E0402020 Nov 27;65(23):23NT02},
      abstract     = {Objective To implement Computed Tomography (CT)-based
                      attenuation maps of radiotherapy (RT) positioning hardware
                      and radiofrequency (RF) coils to enable hybrid positron
                      emission tomography/magnetic resonance imaging
                      (PET/MRI)-based RT treatment planning. Materials and Methods
                      The RT positioning hardware consisted of a flat RT table
                      overlay, coil holders for abdominal scans, coil holders for
                      head and neck scans and an MRI compatible hip and leg
                      immobilization system. CT images of each hardware element
                      were acquired on a CT scanner. Based on the CT images,
                      attenuation maps of the devices were created. Validation
                      measurements were performed on a PET/MR scanner using a 68Ge
                      phantom (48 MBq, 10 min scan time). Scans with each device
                      in treatment position were performed. Then, reference scans
                      containing only the phantom were taken. The scans were
                      reconstructed online (at the PET/MRI scanner) and offline
                      (via e7tools on a PC) using identical reconstruction
                      parameters. Average reconstructed activity concentrations of
                      the device and reference scans were compared. Results The
                      device attenuation maps were successfully implemented. The
                      RT positioning devices caused an average decrease of
                      reconstructed PET activity concentration in the range
                      between -8.3 ± 2.1 $\%$ (mean ± SD) (head and neck coil
                      holder with coils) to -1.0 ± 0.5 $\%$ (abdominal coil
                      holder). With attenuation correction taking into account RT
                      hardware, these values were reduced to -2.0 ± 1.2 $\%$ and
                      0.6 ± 0.5 $\%,$ respectively. The results of the offline
                      and online reconstructions were nearly identical, with a
                      difference of up to 0.2 $\%.$ Conclusion The decrease in
                      reconstructed activity concentration caused by the RT
                      positioning devices is clinically relevant and can
                      successfully be corrected using CT-based attenuation maps.
                      Both the offline and online reconstruction methods are
                      viable options.},
      cin          = {E040 / E025 / E010 / DD01},
      ddc          = {530},
      cid          = {I:(DE-He78)E040-20160331 / I:(DE-He78)E025-20160331 /
                      I:(DE-He78)E010-20160331 / I:(DE-He78)DD01-20160331},
      pnm          = {315 - Imaging and radiooncology (POF3-315)},
      pid          = {G:(DE-HGF)POF3-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32916667},
      doi          = {10.1088/1361-6560/abb7c3},
      url          = {https://inrepo02.dkfz.de/record/163182},
}