TY  - JOUR
AU  - Thomsen, Hauke
AU  - Li, Xinjun
AU  - Sundquist, Kristina
AU  - Sundquist, Jan
AU  - Försti, Asta
AU  - Hemminki, Kari
TI  - Familial associations between autoimmune hepatitis and primary biliary cholangitis and other autoimmune diseases.
JO  - PLOS ONE
VL  - 15
IS  - 10
SN  - 1932-6203
CY  - San Francisco, California, US
PB  - PLOS
M1  - DKFZ-2020-02272
SP  - e0240794 -
PY  - 2020
N1  - #EA:C050#LA:C050#LA:C020#
AB  - Autoimmune hepatitis (AH) and primary biliary cirrhosis (PBC) are autoimmune diseases (AIDs) targeting cellular components of the liver. Being rare diseases, limited data are available about familial risks among these AIDs (concordant) or between them and other AIDs (discordant). We aimed to carry out an unbiased study on these AIDs based on medically diagnosed patients. We collected data on patients diagnosed in Swedish hospitals with AH, PBC and other AIDs and calculated familial standardized incidence ratios (SIRs) for concordant and discordant familial relative risks. The number of AH patients was 6,269, of whom 43.0
LB  - PUB:(DE-HGF)16
C6  - pmid:33079961
DO  - DOI:10.1371/journal.pone.0240794
UR  - https://inrepo02.dkfz.de/record/164132
ER  -