TY  - JOUR
AU  - Mukama, Trasias
AU  - Fallah, Mahdi
AU  - Brenner, Hermann
AU  - Xu, Xing
AU  - Sundquist, Kristina
AU  - Sundquist, Jan
AU  - Kharazmi, Elhamalsadat
TI  - Risk of invasive breast cancer in relatives of patients with breast carcinoma in situ: a prospective cohort study.
JO  - BMC medicine
VL  - 18
IS  - 1
SN  - 1741-7015
CY  - Heidelberg [u.a.]
PB  - Springer
M1  - DKFZ-2020-02400
SP  - 295
PY  - 2020
N1  - #EA:C120#LA:C120#
AB  - Wide implementation of mammography screening has resulted in increased numbers of women diagnosed with breast carcinoma in situ. We aimed to determine the risk of invasive breast cancer in relatives of patients with breast carcinoma in situ in comparison to the risk in relatives of patients with invasive breast cancer.We analyzed the occurrence of cancer in a nationwide cohort including all 5,099,172 Swedish women born after 1931 with at least one known first-degree relative. This was a record linkage study of Swedish family cancer datasets, including cancer registry data collected from January 1, 1958, to December 31, 2015. We calculated standardized incidence ratios (SIRs) and 10-year cumulative risk of breast cancer diagnosis for women with a family history of in situ and invasive breast cancer.Having one first-degree relative with breast carcinoma in situ was associated with 50
LB  - PUB:(DE-HGF)16
C6  - pmid:33148280
C2  - pmc:PMC7643418
DO  - DOI:10.1186/s12916-020-01772-x
UR  - https://inrepo02.dkfz.de/record/165820
ER  -