%0 Journal Article
%A Gillmann, Clarissa
%A Homolka, Noa
%A Johnen, Wibke
%A Runz, Armin
%A Echner, Gernot
%A Pfaffenberger, Asja
%A Mann, Philipp
%A Schneider, Verena
%A Hoffmann, Aswin L
%A Troost, Esther
%A Koerber, Stefan A
%A Kotzerke, Jörg
%A Beuthien-Baumann, Bettina
%T Technical note: ADAM PETer - an anthropomorphic, deformable and multimodality pelvis phantom with position emission tomography extension for radiotherapy.
%J Medical physics
%V 48
%N 4
%@ 2473-4209
%C College Park, Md.
%I AAPM
%M DKFZ-2020-02497
%P 1624-1632
%D 2021
%Z 2021 Apr;48(4):1624-1632#EA:E040#LA:E010#
%X To develop an anthropomorphic, deformable and multimodal pelvis phantom with positron emission tomography extension for radiotherapy (ADAM PETer).The design of ADAM PETer was based on our previous pelvis phantom (ADAM) and extended for compatibility with PET and use in 3T magnetic resonance imaging (MRI). The formerly manually manufactured silicon organ surrogates were replaced by 3D printed organ shells. Two intraprostatic lesions, four iliac lymph node metastases and two pelvic bone metastases were added to simulate prostate cancer as multifocal and metastatic disease. Radiological properties (computed tomography (CT) and 3T MRI) of cortical bone, bone marrow and adipose tissue were simulated by heavy gypsum, a mixture of Vaseline and K2 HPO4 and peanut oil, respectively. For soft tissues, agarose gels with varying concentrations of agarose, gadolinium (Gd) and sodium fluoride (NaF) were developed. The agarose gels were doped with patient-specific activity concentrations of a Fluorine-18 labelled compound and then filled into the 3D printed organ shells of prostate lesions, lymph node and bone metastases. The phantom was imaged at a dual energy CT and a 3T PET/MRI scanner.The compositions of the soft tissue surrogates are the following (given as mass fractions of agarose[w
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:33207020
%R 10.1002/mp.14597
%U https://inrepo02.dkfz.de/record/165948