TY - JOUR AU - Thomsen, Hauke AU - Li, Xinjun AU - Sundquist, Kristina AU - Sundquist, Jan AU - Försti, Asta AU - Hemminki, Kari TI - Familial associations for rheumatoid autoimmune diseases. JO - Rheumatology advances in practice VL - 4 IS - 2 SN - 2514-1775 CY - Oxford PB - Oxford University Press M1 - DKFZ-2020-02588 SP - rkaa048 PY - 2020 N1 - #EA:C050#LA:C050#LA:C020# AB - Previous studies have shown a familial component in RA and in some other rheumatic autoimmune diseases (RAIDs), but because of the different study designs the risk estimates for familial risks differ extensively. The objective of this study is to identify familial components for RAIDs.We collected data on patients diagnosed in Swedish hospitals with RA, AS, PM/DM, SS, SLE and SSc (and scleroderma) and calculated familial standardized incidence ratios (SIRs) for each of these (concordant) and between them (discordant).The combined number of RAID patients in the offspring population (for whom SIRs were calculated) was 71 544, and in the whole population the number was 152 714, accounting for 19.8 LB - PUB:(DE-HGF)16 C6 - pmid:33241174 C2 - pmc:PMC7673201 DO - DOI:10.1093/rap/rkaa048 UR - https://inrepo02.dkfz.de/record/166049 ER -