% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{ZamoraRos:166201,
      author       = {R. Zamora-Ros and L. Lujan-Barroso and D. Achaintre and S.
                      Franceschi and C. Kyrø and K. Overvad and A. Tjønneland
                      and T. Truong and L. Lecuyer and M.-C. Boutron-Ruault and V.
                      Katzke$^*$ and T. S. Johnson$^*$ and M. B. Schulze and A.
                      Trichopoulou and E. Peppa and C. La Vechia and G. Masala and
                      V. Pala and S. Panico and R. Tumino and F. Ricceri and G.
                      Skeie and J. R. Quirós and M. Rodriguez-Barranco and P.
                      Amiano and M.-D. Chirlaque and E. Ardanaz and M. Almquist
                      and J. Hennings and R. Vermeulen and N. J. Wareham and T. Y.
                      N. Tong and D. Aune and G. Byrnes and E. Weiderpass and A.
                      Scalbert and S. Rinaldi and A. Agudo},
      title        = {{B}lood polyphenol concentrations and differentiated
                      thyroid carcinoma in women from the {E}uropean {P}rospective
                      {I}nvestigation into {C}ancer and {N}utrition ({EPIC})
                      study.},
      journal      = {The American journal of clinical nutrition},
      volume       = {113},
      number       = {1},
      issn         = {1938-3207},
      address      = {Oxford},
      publisher    = {Oxford University Press},
      reportid     = {DKFZ-2020-02703},
      pages        = {162-171},
      year         = {2021},
      note         = {Volume 113, Issue 1, January 2021, Pages 162–171,},
      abstract     = {Polyphenols are natural compounds with anticarcinogenic
                      properties in cellular and animal models, but
                      epidemiological evidence determining the associations of
                      these compounds with thyroid cancer (TC) is lacking.The aim
                      of this study was to evaluate the relations between blood
                      concentrations of 36 polyphenols and TC risk in EPIC (the
                      European Prospective Investigation into Cancer and
                      Nutrition).A nested case-control study was conducted on 273
                      female cases (210 papillary, 45 follicular, and 18 not
                      otherwise specified TC tumors) and 512 strictly matched
                      controls. Blood polyphenol concentrations were analyzed by
                      HPLC coupled to tandem MS after enzymatic hydrolysis.Using
                      multivariable-adjusted conditional logistic regression
                      models, caffeic acid (ORlog2: 0.55; $95\%$ CI: 0.33, 0.93)
                      and its dehydrogenated metabolite,
                      3,4-dihydroxyphenylpropionic acid (ORlog2: 0.84; $95\%$ CI:
                      0.71, 0.99), were inversely associated with differentiated
                      TC risk. Similar results were observed for papillary TC, but
                      not for follicular TC. Ferulic acid was also inversely
                      associated only with papillary TC (ORlog2: 0.68; $95\%$ CI:
                      0.51, 0.91). However, none of these relations was
                      significant after Bonferroni correction for multiple
                      testing. No association was observed for any of the
                      remaining polyphenols with total differentiated, papillary,
                      or follicular TC.Blood polyphenol concentrations were mostly
                      not associated with differentiated TC risk in women,
                      although our study raises the possibility that high blood
                      concentrations of caffeic, 3,4-dihydroxyphenylpropionic, and
                      ferulic acids may be related to a lower papillary TC risk.},
      cin          = {C020},
      ddc          = {570},
      cid          = {I:(DE-He78)C020-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:33021645},
      doi          = {10.1093/ajcn/nqaa277},
      url          = {https://inrepo02.dkfz.de/record/166201},
}