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@ARTICLE{Weller:166311,
author = {M. Weller and M. van den Bent and M. Preusser and E. Le
Rhun and J. C. Tonn and G. Minniti and M. Bendszus and C.
Balana and O. Chinot and L. Dirven and P. French and M. E.
Hegi and A. S. Jakola and M. Platten$^*$ and P. Roth and R.
Rudà and S. Short and M. Smits and M. J. B. Taphoorn and A.
von Deimling$^*$ and M. Westphal and R. Soffietti and G.
Reifenberger$^*$ and W. Wick$^*$},
title = {{EANO} guidelines on the diagnosis and treatment of diffuse
gliomas of adulthood.},
journal = {Nature reviews / Clinical oncology},
volume = {18},
number = {3},
issn = {1759-4782},
address = {New York, NY},
publisher = {Nature Publ. Group},
reportid = {DKFZ-2020-02804},
pages = {170-186},
year = {2021},
note = {#LA:B320#2021 Mar;18(3):170-186},
abstract = {In response to major changes in diagnostic algorithms and
the publication of mature results from various large
clinical trials, the European Association of Neuro-Oncology
(EANO) recognized the need to provide updated guidelines for
the diagnosis and management of adult patients with diffuse
gliomas. Through these evidence-based guidelines, a task
force of EANO provides recommendations for the diagnosis,
treatment and follow-up of adult patients with diffuse
gliomas. The diagnostic component is based on the 2016
update of the WHO Classification of Tumors of the Central
Nervous System and the subsequent recommendations of the
Consortium to Inform Molecular and Practical Approaches to
CNS Tumour Taxonomy - Not Officially WHO (cIMPACT-NOW). With
regard to therapy, we formulated recommendations based on
the results from the latest practice-changing clinical
trials and also provide guidance for neuropathological and
neuroradiological assessment. In these guidelines, we define
the role of the major treatment modalities of surgery,
radiotherapy and systemic pharmacotherapy, covering current
advances and cognizant that unnecessary interventions and
expenses should be avoided. This document is intended to be
a source of reference for professionals involved in the
management of adult patients with diffuse gliomas, for
patients and caregivers, and for health-care providers.},
subtyp = {Review Article},
cin = {D170 / HD01 / B300 / ED01 / B320},
ddc = {610},
cid = {I:(DE-He78)D170-20160331 / I:(DE-He78)HD01-20160331 /
I:(DE-He78)B300-20160331 / I:(DE-He78)ED01-20160331 /
I:(DE-He78)B320-20160331},
pnm = {312 - Funktionelle und strukturelle Genomforschung
(POF4-312)},
pid = {G:(DE-HGF)POF4-312},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:33293629},
doi = {10.1038/s41571-020-00447-z},
url = {https://inrepo02.dkfz.de/record/166311},
}