TY  - JOUR
AU  - Adolph, Jonas E
AU  - Fleischhack, Gudrun
AU  - Mikasch, Ruth
AU  - Zeller, Julia
AU  - Warmuth-Metz, Monika
AU  - Bison, Brigitte
AU  - Mynarek, Martin
AU  - Rutkowski, Stefan
AU  - Schüller, Ulrich
AU  - von Hoff, Katja
AU  - Obrecht, Denise
AU  - Pietsch, Torsten
AU  - Pfister, Stefan M
AU  - Pajtler, Kristian W
AU  - Witt, Olaf
AU  - Witt, Hendrik
AU  - Kortmann, Rolf-Dieter
AU  - Timmermann, Beate
AU  - Krauß, Jürgen
AU  - Frühwald, Michael C
AU  - Faldum, Andreas
AU  - Kwiecien, Robert
AU  - Bode, Udo
AU  - Tippelt, Stephan
TI  - Local and Systemic Therapy of Recurrent Ependymoma in Children and Adolescents: Short- and Long-term Results of the E-HIT-REZ 2005 Study.
JO  - Neuro-Oncology
VL  - 23
IS  - 6
SN  - 1523-5866
CY  - Oxford
PB  - Oxford Univ. Press
M1  - DKFZ-2020-02949
SP  - 1012-1023
PY  - 2021
N1  - 2021 Jun 1;23(6):1012-1023
AB  - Survival in recurrent ependymomas in children and adolescents mainly depends on the extent of resection. Studies on repeated radiotherapy and chemotherapy at relapse have shown conflicting results.Using data from the German multi-center E-HIT-REZ-2005 study, we examined the role of local therapy and the efficacy of chemotherapy with blockwise temozolomide (TMZ) in children and adolescents with recurrent ependymomas.53 patients with a median age of 6.9 years (1.25-25.4) at 1 st recurrence and a median follow-up time of 36 months (2-115) were recruited. Gross and near total resection (GTR/NTR) were achieved in 34 (64.2
KW  - chemotherapy (Other)
KW  - ependymoma (Other)
KW  - radiotherapy (Other)
KW  - relapse (Other)
KW  - tumor resection (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:33331885
DO  - DOI:10.1093/neuonc/noaa276
UR  - https://inrepo02.dkfz.de/record/166506
ER  -