guest ::
| Home > Publications database > Lenalidomide versus bortezomib maintenance after frontline autologous stem cell transplantation for multiple myeloma. > print |
| Home > Publications database > Lenalidomide versus bortezomib maintenance after frontline autologous stem cell transplantation for multiple myeloma. > print |
| 001 | 166717 | ||
| 005 | 20240229133528.0 | ||
| 024 | 7 | _ | |a 10.1038/s41408-020-00390-3 |2 doi |
| 024 | 7 | _ | |a pmid:33414374 |2 pmid |
| 024 | 7 | _ | |a altmetric:97296931 |2 altmetric |
| 037 | _ | _ | |a DKFZ-2021-00064 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Baertsch, Marc-Andrea |0 0000-0002-4000-6904 |b 0 |
| 245 | _ | _ | |a Lenalidomide versus bortezomib maintenance after frontline autologous stem cell transplantation for multiple myeloma. |
| 260 | _ | _ | |a London [u.a.] |c 2021 |b Nature Publishing Group |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1610440870_25477 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a Lenalidomide (LEN) maintenance (MT) post autologous stem cell transplantation (ASCT) is standard of care in newly diagnosed multiple myeloma (MM) but has not been compared to other agents in clinical trials. We retrospectively compared bortezomib (BTZ; n = 138) or LEN (n = 183) MT from two subsequent GMMG phase III trials. All patients received three cycles of BTZ-based triplet induction and post-ASCT MT. BTZ MT (1.3 mg/m2 i.v.) was administered every 2 weeks for 2 years. LEN MT included two consolidation cycles (25 mg p.o., days 1-21 of 28 day cycles) followed by 10-15 mg/day for 2 years. The BTZ cohort more frequently received tandem ASCT (91% vs. 33%) due to different tandem ASCT strategies. In the LEN and BTZ cohort, 43% and 46% of patients completed 2 years of MT as intended (p = 0.57). Progression-free survival (PFS; HR = 0.83, p = 0.18) and overall survival (OS; HR = 0.70, p = 0.15) did not differ significantly with LEN vs. BTZ MT. Patients with |
| 536 | _ | _ | |a 313 - Krebsrisikofaktoren und Prävention (POF4-313) |0 G:(DE-HGF)POF4-313 |c POF4-313 |x 0 |f POF IV |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
| 700 | 1 | _ | |a Mai, Elias K |0 0000-0002-6226-1252 |b 1 |
| 700 | 1 | _ | |a Hielscher, Thomas |0 P:(DE-He78)743a4a82daab55306a2c88b9f6bf8c2f |b 2 |u dkfz |
| 700 | 1 | _ | |a Bertsch, Uta |b 3 |
| 700 | 1 | _ | |a Salwender, Hans J |b 4 |
| 700 | 1 | _ | |a Munder, Markus |b 5 |
| 700 | 1 | _ | |a Fuhrmann, Stephan |0 0000-0002-7785-2565 |b 6 |
| 700 | 1 | _ | |a Dührsen, Ulrich |b 7 |
| 700 | 1 | _ | |a Brossart, Peter |b 8 |
| 700 | 1 | _ | |a Neben, Kai |b 9 |
| 700 | 1 | _ | |a Schlenzka, Jana |b 10 |
| 700 | 1 | _ | |a Kunz, Christina |b 11 |
| 700 | 1 | _ | |a Raab, Marc S |b 12 |
| 700 | 1 | _ | |a Hillengaß, Jens |b 13 |
| 700 | 1 | _ | |a Jauch, Anna |b 14 |
| 700 | 1 | _ | |a Seckinger, Anja |b 15 |
| 700 | 1 | _ | |a Hose, Dirk |b 16 |
| 700 | 1 | _ | |a Luntz, Steffen |b 17 |
| 700 | 1 | _ | |a Sonneveld, Pieter |b 18 |
| 700 | 1 | _ | |a Lokhorst, Henk |b 19 |
| 700 | 1 | _ | |a Martin, Hans |b 20 |
| 700 | 1 | _ | |a Goerner, Martin |b 21 |
| 700 | 1 | _ | |a Hoffmann, Martin |b 22 |
| 700 | 1 | _ | |a Lindemann, Hans-Walter |b 23 |
| 700 | 1 | _ | |a Bernhard, Helga |b 24 |
| 700 | 1 | _ | |a Blau, Igor W |b 25 |
| 700 | 1 | _ | |a Scheid, Christof |b 26 |
| 700 | 1 | _ | |a Besemer, Britta |b 27 |
| 700 | 1 | _ | |a Weisel, Katja C |0 0000-0001-9422-6614 |b 28 |
| 700 | 1 | _ | |a Hänel, Mathias |b 29 |
| 700 | 1 | _ | |a Dürig, Jan |b 30 |
| 700 | 1 | _ | |a Goldschmidt, Hartmut |b 31 |
| 700 | 1 | _ | |a Group, German-Speaking Myeloma Multicenter |b 32 |e Collaboration Author |
| 773 | _ | _ | |a 10.1038/s41408-020-00390-3 |g Vol. 11, no. 1, p. 1 |0 PERI:(DE-600)2600560-8 |n 1 |p 1 |t Blood cancer journal |v 11 |y 2021 |x 2044-5385 |
| 909 | C | O | |o oai:inrepo02.dkfz.de:166717 |p VDB |
| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 2 |6 P:(DE-He78)743a4a82daab55306a2c88b9f6bf8c2f |
| 913 | 0 | _ | |a DE-HGF |b Gesundheit |l Krebsforschung |1 G:(DE-HGF)POF3-310 |0 G:(DE-HGF)POF3-313 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-300 |4 G:(DE-HGF)POF |v Cancer risk factors and prevention |x 0 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Krebsforschung |1 G:(DE-HGF)POF4-310 |0 G:(DE-HGF)POF4-313 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-300 |4 G:(DE-HGF)POF |v Krebsrisikofaktoren und Prävention |x 0 |
| 914 | 1 | _ | |y 2021 |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b BLOOD CANCER J : 2018 |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0320 |2 StatID |b PubMed Central |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0501 |2 StatID |b DOAJ Seal |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0500 |2 StatID |b DOAJ |d 2020-09-05 |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b DOAJ : Blind peer review |d 2020-09-05 |
| 915 | _ | _ | |a Creative Commons Attribution CC BY (No Version) |0 LIC:(DE-HGF)CCBYNV |2 V:(DE-HGF) |b DOAJ |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0160 |2 StatID |b Essential Science Indicators |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1110 |2 StatID |b Current Contents - Clinical Medicine |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1190 |2 StatID |b Biological Abstracts |d 2020-09-05 |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0113 |2 StatID |b Science Citation Index Expanded |d 2020-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |d 2020-09-05 |
| 915 | _ | _ | |a IF >= 5 |0 StatID:(DE-HGF)9905 |2 StatID |b BLOOD CANCER J : 2018 |d 2020-09-05 |
| 915 | _ | _ | |a Article Processing Charges |0 StatID:(DE-HGF)0561 |2 StatID |d 2020-09-05 |
| 915 | _ | _ | |a Fees |0 StatID:(DE-HGF)0700 |2 StatID |d 2020-09-05 |
| 920 | 1 | _ | |0 I:(DE-He78)C060-20160331 |k C060 |l C060 Biostatistik |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-He78)C060-20160331 |
| 980 | _ | _ | |a UNRESTRICTED |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|