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@ARTICLE{Jarraya:166793,
      author       = {M. Jarraya and R. Heiss and J. Duryea and A. M. Nagel$^*$
                      and J. A. Lynch and A. Guermazi and M.-A. Weber and A.
                      Arkudas and R. E. Horch and M. Uder and F. W. Roemer},
      title        = {{B}one {S}tructure {A}nalysis of the {R}adius {U}sing
                      {U}ltrahigh {F}ield (7{T}) {MRI}: {R}elevance of {T}echnical
                      {P}arameters and {C}omparison with 3{T} {MRI} and
                      {R}adiography.},
      journal      = {Diagnostics},
      volume       = {11},
      number       = {1},
      issn         = {2075-4418},
      address      = {Basel},
      publisher    = {MDPI},
      reportid     = {DKFZ-2021-00123},
      pages        = {110},
      year         = {2021},
      abstract     = {Bone fractal signature analysis (FSA-also termed bone
                      texture analysis) is a tool that assesses structural changes
                      that may relate to clinical outcomes and functions. Our aim
                      was to compare bone texture analysis of the distal radius in
                      patients and volunteers using radiography and 3T and 7T
                      magnetic resonance imaging (MRI)-a patient group (n = 25)
                      and a volunteer group (n = 25) were included. Participants
                      in the patient group had a history of chronic wrist pain
                      with suspected or confirmed osteoarthritis and/or ligament
                      instability. All participants had 3T and 7T MRI including
                      T1-weighted turbo spin echo (TSE) sequences. The 7T MRI
                      examination included an additional high-resolution (HR) T1
                      TSE sequence. Radiographs of the wrist were acquired for the
                      patient group. When comparing patients and volunteers
                      (unadjusted for gender and age), we found a statistically
                      significant difference of horizontal and vertical fractal
                      dimensions (FDs) using 7T T1 TSE-HR images in low-resolution
                      mode (horizontal: p = 0.04, vertical: p = 0.01). When
                      comparing radiography to the different MRI sequences, we
                      found a statistically significant difference for low- and
                      high-resolution horizontal FDs between radiography and 3T T1
                      TSE and 7T T1 TSE-HR. Vertical FDs were significantly
                      different only between radiographs and 3T T1 TSE in the
                      high-resolution mode; FSA measures obtained from 3T and 7T
                      MRI are highly dependent on the sequence and reconstruction
                      resolution used, and thus are not easily comparable between
                      MRI systems and applied sequences.},
      keywords     = {MRI (Other) / X-ray (Other) / bone structure (Other) /
                      fractal signature analysis (Other) / wrist (Other)},
      cin          = {E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E020-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:33445536},
      doi          = {10.3390/diagnostics11010110},
      url          = {https://inrepo02.dkfz.de/record/166793},
}