000167329 001__ 167329
000167329 005__ 20240909140820.0
000167329 0247_ $$2doi$$a10.1039/D0OB02513E
000167329 0247_ $$2pmid$$apmid:33527964
000167329 0247_ $$2ISSN$$a1477-0520
000167329 0247_ $$2ISSN$$a1477-0539
000167329 037__ $$aDKFZ-2021-00277
000167329 041__ $$aeng
000167329 082__ $$a540
000167329 1001_ $$0P:(DE-He78)c53db83479d3d1265967405af71f69bb$$aKlika, Karel$$b0$$eFirst author$$udkfz
000167329 245__ $$aSynthesis and application of a thiol-reactive HBED-type chelator for development of easy-to-produce Ga-radiopharmaceutical kits and imaging probes.
000167329 260__ $$aCambridge$$bRoyal Society of Chemistry$$c2021
000167329 3367_ $$2DRIVER$$aarticle
000167329 3367_ $$2DataCite$$aOutput Types/Journal article
000167329 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1725883665_24152
000167329 3367_ $$2BibTeX$$aARTICLE
000167329 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000167329 3367_ $$00$$2EndNote$$aJournal Article
000167329 500__ $$a#EA:A390#LA:E030# /Division of Radiopharmaceutical Chemistry,2021 Mar 4;19(8):1722-1726
000167329 520__ $$aIn radiopharmaceutical syntheses, maleimide is commonly used for linking thiol-bearing bioactive molecules to metal-complexing ligands (chelators). However, due to instability of the resulting linkage, phenyloxadiazolyl methylsulfone (PODS) was developed as an alternative to maleimide. This coupling strategy has never been attempted with HBED which is a powerful chelator for gallium-radiolabeling especially at ambient temperature. Here we present HBED-CC-PODS as a bifunctional chelator scaffold for the site-selective conjugation of thiol-bearing vectors and [68Ga]Ga-radiolabeling.
000167329 536__ $$0G:(DE-HGF)POF4-315$$a315 - Bildgebung und Radioonkologie (POF4-315)$$cPOF4-315$$fPOF IV$$x0
000167329 588__ $$aDataset connected to CrossRef, PubMed,
000167329 7001_ $$aDa Pieve, Chiara$$b1
000167329 7001_ $$aKopka, Klaus$$b2
000167329 7001_ $$aSmith, Graham$$b3
000167329 7001_ $$0P:(DE-He78)e5df498f08a8708fc5b826f0eca1db41$$aMakarem, Ata$$b4$$eLast author$$udkfz
000167329 773__ $$0PERI:(DE-600)2097583-1$$a10.1039/D0OB02513E$$gp. 10.1039.D0OB02513E$$n8$$p1722-1726$$tOrganic & biomolecular chemistry$$v19$$x1477-0539$$y2021
000167329 909CO $$ooai:inrepo02.dkfz.de:167329$$pVDB
000167329 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)c53db83479d3d1265967405af71f69bb$$aDeutsches Krebsforschungszentrum$$b0$$kDKFZ
000167329 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)e5df498f08a8708fc5b826f0eca1db41$$aDeutsches Krebsforschungszentrum$$b4$$kDKFZ
000167329 9131_ $$0G:(DE-HGF)POF4-315$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vBildgebung und Radioonkologie$$x0
000167329 9130_ $$0G:(DE-HGF)POF3-311$$1G:(DE-HGF)POF3-310$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vSignalling pathways, cell and tumor biology$$x0
000167329 9141_ $$y2021
000167329 915__ $$0StatID:(DE-HGF)0400$$2StatID$$aAllianz-Lizenz / DFG$$d2020-08-21$$wger
000167329 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2020-08-21$$wger
000167329 915__ $$0StatID:(DE-HGF)0430$$2StatID$$aNational-Konsortium$$d2020-08-21$$wger
000167329 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)1200$$2StatID$$aDBCoverage$$bChemical Reactions$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)1150$$2StatID$$aDBCoverage$$bCurrent Contents - Physical, Chemical and Earth Sciences$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)1210$$2StatID$$aDBCoverage$$bIndex Chemicus$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bORG BIOMOL CHEM : 2018$$d2020-08-21
000167329 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2020-08-21
000167329 9202_ $$0I:(DE-He78)E030-20160331$$kE030$$lRadiopharmazeutische Chemie$$x0
000167329 9201_ $$0I:(DE-He78)A390-20160331$$kA390$$lAG Wirkstoffforschung$$x0
000167329 9201_ $$0I:(DE-He78)E030-20160331$$kE030$$lRadiopharmazeutische Chemie$$x1
000167329 9200_ $$0I:(DE-He78)A390-20160331$$kA390$$lAG Wirkstoffforschung$$x0
000167329 980__ $$ajournal
000167329 980__ $$aVDB
000167329 980__ $$aI:(DE-He78)A390-20160331
000167329 980__ $$aI:(DE-He78)E030-20160331
000167329 980__ $$aUNRESTRICTED