TY  - JOUR
AU  - Rehm, Martin
AU  - Büchele, Gisela
AU  - Brenner, Rolf Erwin
AU  - Günther, Klaus-Peter
AU  - Brenner, Hermann
AU  - Koenig, Wolfgang
AU  - Rothenbacher, Dietrich
TI  - Repeated Measurements of Cardiac Troponin T and N-Terminal Pro-B-Type Natriuretic Peptide to Assess Long-Term Mortality Risk in Subjects with Osteoarthritis.
JO  - Biomolecules
VL  - 11
IS  - 2
SN  - 2218-273X
CY  - Basel
PB  - MDPI
M1  - DKFZ-2021-00339
SP  - 230
PY  - 2021
AB  - Osteoarthritis (OA) is associated with higher cardiovascular mortality risk. High-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are well-characterized prognostic cardiac markers. We aimed to describe the changes in biomarkers measured one year apart in a cohort of 347 subjects with OA who underwent hip or knee replacement surgery in 1995/1996 and to analyze the prognostic value of repeated measurements for long-term mortality. During a median follow-up of 19 years, 209 (60.2
KW  - N-terminal pro-B-type natriuretic peptide (NT-proBNP) (Other)
KW  - cohort study (Other)
KW  - high-sensitivity cardiac troponin T (hs-cTnT) (Other)
KW  - mortality (Other)
KW  - osteoarthritis (Other)
KW  - repeated measurements (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:33562838
DO  - DOI:10.3390/biom11020230
UR  - https://inrepo02.dkfz.de/record/167435
ER  -