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@ARTICLE{Behjati:167485,
      author       = {S. Behjati and R. J. Gilbertson and S. Pfister$^*$},
      title        = {{M}aturation {B}lock in {C}hildhood {C}ancer.},
      journal      = {Cancer discovery},
      volume       = {11},
      number       = {3},
      issn         = {2159-8290},
      address      = {Philadelphia, Pa.},
      reportid     = {DKFZ-2021-00386},
      pages        = {542-544},
      year         = {2021},
      note         = {#LA:B062#2021 Mar;11(3):542-544},
      abstract     = {The key differences between tumors arising in children and
                      those in adults stem from the cellular origin of cancer at
                      different ages, with adult cancers arising within aging cell
                      hierarchies, as a consequence of accumulated damage and
                      mutagenesis, in contrast to childhood tumors that are born
                      in aberrantly developing tissues. A distinct biological
                      property of childhood tumor cells-a block of developmental
                      maturation-may hold the key to advancing the treatment of
                      childhood cancer beyond cytotoxic strategies.},
      cin          = {B062 / HD01},
      ddc          = {610},
      cid          = {I:(DE-He78)B062-20160331 / I:(DE-He78)HD01-20160331},
      pnm          = {312 - Funktionelle und strukturelle Genomforschung
                      (POF4-312)},
      pid          = {G:(DE-HGF)POF4-312},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:33589423},
      doi          = {10.1158/2159-8290.CD-20-0926},
      url          = {https://inrepo02.dkfz.de/record/167485},
}