TY  - JOUR
AU  - Mukama, Trasias
AU  - Kharazmi, Elham
AU  - Sundquist, Kristina
AU  - Sundquist, Jan
AU  - Fallah, Mahdi
TI  - Risk-adapted starting age of breast cancer screening in women with a family history of ovarian or other cancers: A nationwide cohort study.
JO  - Cancer
VL  - 127
IS  - 12
SN  - 0008-543X
CY  - New York, NY
PB  - Wiley-Liss
M1  - DKFZ-2021-00447
SP  - 2091-2098
PY  - 2021
N1  - #EA:C120#LA:C120# / 127(12):2091-2098
AB  - There is a lack of evidence-based recommendations for the age at which women with a family history of cancers other than breast cancer should start breast cancer screening.Using Swedish family cancer data sets, the authors conducted a nationwide cohort study including 5,099,172 Swedish women born after 1931 (follow-up, 1958-2015). Accounting for calendar time, they calculated the relative risk of breast cancer for women with a family history of a discordant cancer in 1 first-degree relative. Furthermore, the authors used 10-year cumulative risk to determine the ages at which women with a family history of discordant cancer reached risk thresholds at which women in the general population were recommended to start breast cancer screening.A family history of cancer at 15 sites was associated with an increased risk of breast cancer. Among women younger than 50 years, the highest risk of breast cancer was observed for those with a family history of ovarian cancer (standardized incidence ratio, 1.44; 95
KW  - breast cancer (Other)
KW  - discordant cancers (Other)
KW  - familial clustering (Other)
KW  - familial risk (Other)
KW  - family history (Other)
KW  - screening (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:33620751
DO  - DOI:10.1002/cncr.33456
UR  - https://inrepo02.dkfz.de/record/167587
ER  -