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@ARTICLE{Mukama:167587,
      author       = {T. Mukama$^*$ and E. Kharazmi$^*$ and K. Sundquist and J.
                      Sundquist and M. Fallah$^*$},
      title        = {{R}isk-adapted starting age of breast cancer screening in
                      women with a family history of ovarian or other cancers: {A}
                      nationwide cohort study.},
      journal      = {Cancer},
      volume       = {127},
      number       = {12},
      issn         = {0008-543X},
      address      = {New York, NY},
      publisher    = {Wiley-Liss},
      reportid     = {DKFZ-2021-00447},
      pages        = {2091-2098},
      year         = {2021},
      note         = {#EA:C120#LA:C120# / 127(12):2091-2098},
      abstract     = {There is a lack of evidence-based recommendations for the
                      age at which women with a family history of cancers other
                      than breast cancer should start breast cancer
                      screening.Using Swedish family cancer data sets, the authors
                      conducted a nationwide cohort study including 5,099,172
                      Swedish women born after 1931 (follow-up, 1958-2015).
                      Accounting for calendar time, they calculated the relative
                      risk of breast cancer for women with a family history of a
                      discordant cancer in 1 first-degree relative. Furthermore,
                      the authors used 10-year cumulative risk to determine the
                      ages at which women with a family history of discordant
                      cancer reached risk thresholds at which women in the general
                      population were recommended to start breast cancer
                      screening.A family history of cancer at 15 sites was
                      associated with an increased risk of breast cancer. Among
                      women younger than 50 years, the highest risk of breast
                      cancer was observed for those with a family history of
                      ovarian cancer (standardized incidence ratio, 1.44; $95\%$
                      confidence interval, 1.26-1.64). In these women, the risk of
                      breast cancer associated with a family history at other
                      cancer sites ranged from 1.08-fold for prostate cancer to
                      1.18-fold for liver cancer. When breast cancer screening was
                      recommended to be started at the age of 50 years for the
                      general population, women with 1 first-degree relative with
                      ovarian cancer attained the threshold risk for screening at
                      the age of 46 years. Women with a family history of other
                      discordant cancers did not reach the risk thresholds for
                      screening at younger ages.Many cancers showed familial
                      associations with breast cancer, but women with a family
                      history of these cancers (except for ovarian cancer) did not
                      reach risk thresholds for screening at younger ages.},
      keywords     = {breast cancer (Other) / discordant cancers (Other) /
                      familial clustering (Other) / familial risk (Other) / family
                      history (Other) / screening (Other)},
      cin          = {C120},
      ddc          = {610},
      cid          = {I:(DE-He78)C120-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:33620751},
      doi          = {10.1002/cncr.33456},
      url          = {https://inrepo02.dkfz.de/record/167587},
}