%0 Journal Article
%A Zheng, Guoqiao
%A Sundquist, Jan
%A Sundquist, Kristina
%A Ji, Jianguang
%T Beta-blockers use and risk of breast cancer in women with hypertension.
%J Cancer epidemiology, biomarkers & prevention
%V 30
%N 5
%@ 1538-7755
%C Philadelphia, Pa.
%I AACR
%M DKFZ-2021-00450
%P 965-973
%D 2021
%Z #EA:C020# / 30(5):965-973
%X The risk of breast cancer among hypertensive patients who use beta-blockers has attracted attention. However, the evidence is inconsistent and investigation of the dose-specific associations for subtypes of beta-blockers are limited.By incorporating Swedish national registers, breast cancer risk was estimated in women with hypertension who used nonselective beta-blockers and beta-1 selective blockers compared with propensity score-matched non-users. The cumulative defined daily dose was used to study the dose-response association. Test of interaction between beta-blocker use and other antihypertensive medications was performed.Hypertensive patients taking beta-1 selective blockers (metoprolol, atenolol, bisoprolol) had an increased risk of breast cancer with a hazard ratio (HR) and 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:33619022
%R 10.1158/1055-9965.EPI-20-1599
%U https://inrepo02.dkfz.de/record/167590