%0 Journal Article %A Adam, Salome %A Thong, Melissa %A Martin-Diener, Eva %A Camey, Bertrand %A Egger Hayoz, Céline %A Konzelmann, Isabelle %A Mousavi, Seyed Mohsen %A Herrmann, Christian %A Rohrmann, Sabine %A Wanner, Miriam %A Staehelin, Katharina %A Strebel, Räto T %A Randazzo, Marco %A John, Hubert %A Schmid, Hans-Peter %A Feller, Anita %A Arndt, Volker %T Identifying classes of the pain, fatigue, and depression symptom cluster in long-term prostate cancer survivors-results from the multi-regional Prostate Cancer Survivorship Study in Switzerland (PROCAS). %J Supportive care in cancer %V 29 %N 11 %@ 1433-7339 %C New York,NY %I Springer %M DKFZ-2021-00858 %P 6259-6269 %D 2021 %Z #LA:C071# / 2021 Nov;29(11):6259-6269 %X Aside from urological and sexual problems, long-term (≥5 years after initial diagnosis) prostate cancer (PC) survivors might suffer from pain, fatigue, and depression. These concurrent symptoms can form a cluster. In this study, we aimed to investigate classes of this symptom cluster in long-term PC survivors, to classify PC survivors accordingly, and to explore associations between classes of this cluster and health-related quality of life (HRQoL).Six hundred fifty-three stage T1-T3N0M0 survivors were identified from the Prostate Cancer Survivorship in Switzerland (PROCAS) study. Fatigue was assessed with the EORTC QLQ-FA12, depressive symptoms with the MHI-5, and pain with the EORTC QLQ-C30 questionnaire. Latent class analysis was used to derive cluster classes. Factors associated with the derived classes were determined using multinomial logistic regression analysis.Three classes were identified: class 1 (61.4 %K Classes (Other) %K Depression (Other) %K Fatigue (Other) %K Pain (Other) %K Prostate cancer (Other) %K Symptom cluster (Other) %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:33847829 %R 10.1007/s00520-021-06132-w %U https://inrepo02.dkfz.de/record/168369