TY - JOUR AU - Adam, Salome AU - Thong, Melissa AU - Martin-Diener, Eva AU - Camey, Bertrand AU - Egger Hayoz, Céline AU - Konzelmann, Isabelle AU - Mousavi, Seyed Mohsen AU - Herrmann, Christian AU - Rohrmann, Sabine AU - Wanner, Miriam AU - Staehelin, Katharina AU - Strebel, Räto T AU - Randazzo, Marco AU - John, Hubert AU - Schmid, Hans-Peter AU - Feller, Anita AU - Arndt, Volker TI - Identifying classes of the pain, fatigue, and depression symptom cluster in long-term prostate cancer survivors-results from the multi-regional Prostate Cancer Survivorship Study in Switzerland (PROCAS). JO - Supportive care in cancer VL - 29 IS - 11 SN - 1433-7339 CY - New York,NY PB - Springer M1 - DKFZ-2021-00858 SP - 6259-6269 PY - 2021 N1 - #LA:C071# / 2021 Nov;29(11):6259-6269 AB - Aside from urological and sexual problems, long-term (≥5 years after initial diagnosis) prostate cancer (PC) survivors might suffer from pain, fatigue, and depression. These concurrent symptoms can form a cluster. In this study, we aimed to investigate classes of this symptom cluster in long-term PC survivors, to classify PC survivors accordingly, and to explore associations between classes of this cluster and health-related quality of life (HRQoL).Six hundred fifty-three stage T1-T3N0M0 survivors were identified from the Prostate Cancer Survivorship in Switzerland (PROCAS) study. Fatigue was assessed with the EORTC QLQ-FA12, depressive symptoms with the MHI-5, and pain with the EORTC QLQ-C30 questionnaire. Latent class analysis was used to derive cluster classes. Factors associated with the derived classes were determined using multinomial logistic regression analysis.Three classes were identified: class 1 (61.4 KW - Classes (Other) KW - Depression (Other) KW - Fatigue (Other) KW - Pain (Other) KW - Prostate cancer (Other) KW - Symptom cluster (Other) LB - PUB:(DE-HGF)16 C6 - pmid:33847829 DO - DOI:10.1007/s00520-021-06132-w UR - https://inrepo02.dkfz.de/record/168369 ER -