000168695 001__ 168695 000168695 005__ 20240229133613.0 000168695 0247_ $$2doi$$a10.3390/nu13041195 000168695 0247_ $$2pmid$$apmid:33916366 000168695 0247_ $$2pmc$$apmc:PMC8067073 000168695 0247_ $$2altmetric$$aaltmetric:103325810 000168695 037__ $$aDKFZ-2021-01003 000168695 041__ $$aEnglish 000168695 082__ $$a610 000168695 1001_ $$0P:(DE-He78)d1572cf10ef7129f68f9c3180954b34c$$aPannen, Sarah$$b0$$eFirst author 000168695 245__ $$aAdherence and Dietary Composition during Intermittent vs. Continuous Calorie Restriction: Follow-Up Data from a Randomized Controlled Trial in Adults with Overweight or Obesity. 000168695 260__ $$aBasel$$bMDPI$$c2021 000168695 3367_ $$2DRIVER$$aarticle 000168695 3367_ $$2DataCite$$aOutput Types/Journal article 000168695 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1620224046_814 000168695 3367_ $$2BibTeX$$aARTICLE 000168695 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000168695 3367_ $$00$$2EndNote$$aJournal Article 000168695 500__ $$a#EA:C020#LA:C020# 000168695 520__ $$aAlthough intermittent calorie restriction (ICR) has become popular as an alternative weight loss strategy to continuous calorie restriction (CCR), there is insufficient evidence on diet quality during ICR and on its feasibility over longer time periods. Thus, we compared dietary composition and adherence between ICR and CCR in a follow-up analysis of a randomized trial. A total of 98 participants with overweight or obesity [BMI (kg/m2) 25-39.9, 35-65 years, 49% females] were randomly assigned to ICR, operationalized as a '5:2 diet' (energy intake: ~100% on five non-restricted (NR) days, ~25% on two restricted (R) days), or CCR (daily energy intake: ~80%). The trial included a 12-week (wk) intervention phase, and follow-up assessments at wk24, wk50 and wk102. Apart from a higher proportion of energy intake from protein with ICR vs. CCR during the intervention (wk2: p < 0.001; wk12: p = 0.002), there were no significant differences with respect to changes in dietary composition over time between the groups, while overall adherence to the interventions appeared to be good. No significant difference between ICR and CCR regarding weight change at wk102 was observed (p = 0.63). However, self-reported adherence was worse for ICR than CCR, with 71.1% vs. 32.5% of the participants reporting not to or only rarely have followed the regimen to which they were assigned between wk50 and wk102. These results indicate that within a weight management setting, ICR and CCR were equivalent in achieving modest weight loss over two years while affecting dietary composition in a comparable manner. 000168695 536__ $$0G:(DE-HGF)POF4-313$$a313 - Krebsrisikofaktoren und Prävention (POF4-313)$$cPOF4-313$$fPOF IV$$x0 000168695 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo01.inet.dkfz-heidelberg.de 000168695 650_7 $$2Other$$acompliance 000168695 650_7 $$2Other$$adiet quality 000168695 650_7 $$2Other$$aenergy intake 000168695 650_7 $$2Other$$afasting 000168695 650_7 $$2Other$$afood records 000168695 650_7 $$2Other$$aintermittent energy restriction 000168695 650_7 $$2Other$$aobesity 000168695 650_7 $$2Other$$aweight loss 000168695 7001_ $$0P:(DE-HGF)0$$aMaldonado, Sandra González$$b1 000168695 7001_ $$0P:(DE-He78)95cbb002ef4aaccc0a2fc6b596110f1a$$aNonnenmacher, Tobias$$b2$$udkfz 000168695 7001_ $$0P:(DE-He78)b4004ee4b650b575447f59a4a0471312$$aSowah, Solomon A$$b3$$udkfz 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