TY  - JOUR
AU  - Hemminki, Kari
AU  - Försti, Asta
AU  - Hemminki, Akseli
AU  - Ljungberg, Börje
AU  - Hemminki, Otto
TI  - Incidence trends in bladder and lung cancers between Denmark, Finland and Sweden may implicate oral tobacco (snuff/snus) as a possible risk factor.
JO  - BMC cancer
VL  - 21
IS  - 1
SN  - 1471-2407
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2021-01169
SP  - 604
PY  - 2021
AB  - The dominant risk factor for urinary bladder cancer has been cigarette smoking, but, as smoking prevalence is decreasing in many populations, other risk factors may become uncovered. Such new risk factors could be responsible for halting the declining incidence of bladder cancer. We hypothesize that snuff use by Swedish men may increase the rate for bladder cancer, as snuff contains carcinogenic nitrosamines.We carried out an ecological study by comparing incidence trends in lung and bladder cancers between Danish, Finnish and Swedish men in order to test if the Swedish bladder cancer rate deviates from the Danish and Finnish ones. We used the NORDCAN database for cancer data from 1960 through 2016 to test the hypothesis.In the three countries, the incidence of lung cancer started to decrease after a peak incidence, and this was later followed by declining incidence in bladder cancer in Denmark from 1990 to 2016 by 14.3
KW  - Incidence trend (Other)
KW  - Risk factors (Other)
KW  - Sex difference (Other)
KW  - Snuffing (Other)
KW  - Tobacco products (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:34034676
DO  - DOI:10.1186/s12885-021-08371-w
UR  - https://inrepo02.dkfz.de/record/168973
ER  -