%0 Journal Article
%A Kratzer, Fabian
%A Flassbeck, Sebastian
%A Schmitter, Sebastian
%A Wilferth, Tobias
%A Magill, Arthur
%A Knowles, Benjamin R
%A Platt, Tanja
%A Bachert, Peter
%A Ladd, Mark E
%A Nagel, Armin
%T 3D sodium (23 Na) magnetic resonance fingerprinting for time-efficient relaxometric mapping.
%J Magnetic resonance in medicine
%V 86
%N 5
%@ 1522-2594
%C New York, NY [u.a.]
%I Wiley-Liss
%M DKFZ-2021-01217
%P 2412-2425
%D 2021
%Z #EA:E020#LA:E020#/ 2021 Nov;86(5):2412-2425
%X To develop a framework for 3D sodium (23 Na) MR fingerprinting (MRF), based on irreducible spherical tensor operators with tailored flip angle (FA) pattern and time-efficient data acquisition for simultaneous quantification of T1 , T 2 l ∗ , T 2 s ∗ , and T 2 ∗ in addition to ΔB0 .23 Na-MRF was implemented in a 3D sequence and irreducible spherical tensor operators were exploited in the simulations. Furthermore, the Cramér Rao lower bound was used to optimize the flip angle pattern. A combination of single and double echo readouts was implemented to increase the readout efficiency. A study was conducted to compare results in a multicompartment phantom acquired with MRF and reference methods. Finally, the relaxation times in the human brain were measured in four healthy volunteers.Phantom experiments revealed a mean difference of 1.0
%K 7 Tesla (Other)
%K Cramér Rao lower bound (Other)
%K X-nuclei (Other)
%K magnetic resonance fingerprinting (Other)
%K relaxometry (Other)
%K sodium (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34061397
%R 10.1002/mrm.28873
%U https://inrepo02.dkfz.de/record/169059