TY  - JOUR
AU  - Kratzer, Fabian
AU  - Flassbeck, Sebastian
AU  - Schmitter, Sebastian
AU  - Wilferth, Tobias
AU  - Magill, Arthur
AU  - Knowles, Benjamin R
AU  - Platt, Tanja
AU  - Bachert, Peter
AU  - Ladd, Mark E
AU  - Nagel, Armin
TI  - 3D sodium (23 Na) magnetic resonance fingerprinting for time-efficient relaxometric mapping.
JO  - Magnetic resonance in medicine
VL  - 86
IS  - 5
SN  - 1522-2594
CY  - New York, NY [u.a.]
PB  - Wiley-Liss
M1  - DKFZ-2021-01217
SP  - 2412-2425
PY  - 2021
N1  - #EA:E020#LA:E020#/ 2021 Nov;86(5):2412-2425
AB  - To develop a framework for 3D sodium (23 Na) MR fingerprinting (MRF), based on irreducible spherical tensor operators with tailored flip angle (FA) pattern and time-efficient data acquisition for simultaneous quantification of T1 , T 2 l ∗ , T 2 s ∗ , and T 2 ∗ in addition to ΔB0 .23 Na-MRF was implemented in a 3D sequence and irreducible spherical tensor operators were exploited in the simulations. Furthermore, the Cramér Rao lower bound was used to optimize the flip angle pattern. A combination of single and double echo readouts was implemented to increase the readout efficiency. A study was conducted to compare results in a multicompartment phantom acquired with MRF and reference methods. Finally, the relaxation times in the human brain were measured in four healthy volunteers.Phantom experiments revealed a mean difference of 1.0
KW  - 7 Tesla (Other)
KW  - Cramér Rao lower bound (Other)
KW  - X-nuclei (Other)
KW  - magnetic resonance fingerprinting (Other)
KW  - relaxometry (Other)
KW  - sodium (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:34061397
DO  - DOI:10.1002/mrm.28873
UR  - https://inrepo02.dkfz.de/record/169059
ER  -