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000169174 1001_ $$0P:(DE-He78)d028533bf57b4053bc9b94b70daab443$$aVedelago, Jose Alberto$$b0$$eFirst author$$udkfz
000169174 245__ $$aSmart material based on boron crosslinked polymers with potential applications in cancer radiation therapy.
000169174 260__ $$a[London]$$bMacmillan Publishers Limited, part of Springer Nature$$c2021
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000169174 520__ $$aOrganoboron compounds have been playing an increasingly important role in analytical chemistry, material science, health applications, and particularly as functional polymers like boron carriers for cancer therapy. There are two main applications of boron isotopes in radiation cancer therapy, Boron Neutron Capture Therapy and Proton Boron Fusion Therapy. In this study, a novel and original material consisting of a three-dimensional polymer network crosslinked with [Formula: see text]B enriched boric acid molecules is proposed and synthesized. The effects of the exposition to thermal neutrons were studied analyzing changes in the mechanical properties of the proposed material. Dedicated Monte Carlo simulations, based on MCNP and FLUKA main codes, were performed to characterize interactions of the proposed material with neutrons, photons, and charged particles typically present in mixed fields in nuclear reactor irradiations. Experimental results and Monte Carlo simulations were in agreement, thus justifying further studies of this promising material.
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000169174 7001_ $$aMattea, Facundo$$b1
000169174 7001_ $$aTriviño, Sebastián$$b2
000169174 7001_ $$aMontesinos, María Del Mar$$b3
000169174 7001_ $$aKeil, Walter$$b4
000169174 7001_ $$aValente, Mauro$$b5
000169174 7001_ $$aRomero, Marcelo$$b6
000169174 773__ $$0PERI:(DE-600)2615211-3$$a10.1038/s41598-021-91413-x$$gVol. 11, no. 1, p. 12269$$n1$$p12269$$tScientific reports$$v11$$x2045-2322$$y2021
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